Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil
We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. After administration of the sleeping pill zopiclone, a nonbenzodiazepine receptor agonist (NBRA), the patien...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2016/3185873 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561075375046656 |
|---|---|
| author | Zarah Jordahn Cheme Andersen Anne Marie Roust Aaberg Frank Christian Pott |
| author_facet | Zarah Jordahn Cheme Andersen Anne Marie Roust Aaberg Frank Christian Pott |
| author_sort | Zarah Jordahn |
| collection | DOAJ |
| description | We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. After administration of the sleeping pill zopiclone, a nonbenzodiazepine receptor agonist (NBRA), the patient became agitated and was confused, a possible paradoxical reaction to benzodiazepines. These symptoms were immediately resolved after treatment with flumazenil, usually used to reverse the adverse effects of benzodiazepines or NBRAs and to reverse paradoxical reactions to benzodiazepines. This case indicates that zopiclone induced behavioral changes resembling a paradoxical reaction to benzodiazepines and these symptoms may be treated with flumazenil. |
| format | Article |
| id | doaj-art-17039b67fdfe4f178c2ea7f4040614b1 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-17039b67fdfe4f178c2ea7f4040614b12025-02-03T01:25:53ZengWileyCase Reports in Critical Care2090-64202090-64392016-01-01201610.1155/2016/31858733185873Reversal of a Suspected Paradoxical Reaction to Zopiclone with FlumazenilZarah Jordahn0Cheme Andersen1Anne Marie Roust Aaberg2Frank Christian Pott3Department of Anaesthesiology, Rigshospitalet, Glostrup Matriklen, Copenhagen, DenmarkDepartment of Anaesthesiology, Copenhagen University Hospital, Hvidovre, DenmarkDepartment of Anaesthesia and Intensive Care, Bispebjerg Hospital, Copenhagen, DenmarkDepartment of Anaesthesia and Intensive Care, Bispebjerg Hospital, Copenhagen, DenmarkWe describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. After administration of the sleeping pill zopiclone, a nonbenzodiazepine receptor agonist (NBRA), the patient became agitated and was confused, a possible paradoxical reaction to benzodiazepines. These symptoms were immediately resolved after treatment with flumazenil, usually used to reverse the adverse effects of benzodiazepines or NBRAs and to reverse paradoxical reactions to benzodiazepines. This case indicates that zopiclone induced behavioral changes resembling a paradoxical reaction to benzodiazepines and these symptoms may be treated with flumazenil.http://dx.doi.org/10.1155/2016/3185873 |
| spellingShingle | Zarah Jordahn Cheme Andersen Anne Marie Roust Aaberg Frank Christian Pott Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil Case Reports in Critical Care |
| title | Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil |
| title_full | Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil |
| title_fullStr | Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil |
| title_full_unstemmed | Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil |
| title_short | Reversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil |
| title_sort | reversal of a suspected paradoxical reaction to zopiclone with flumazenil |
| url | http://dx.doi.org/10.1155/2016/3185873 |
| work_keys_str_mv | AT zarahjordahn reversalofasuspectedparadoxicalreactiontozopiclonewithflumazenil AT chemeandersen reversalofasuspectedparadoxicalreactiontozopiclonewithflumazenil AT annemarieroustaaberg reversalofasuspectedparadoxicalreactiontozopiclonewithflumazenil AT frankchristianpott reversalofasuspectedparadoxicalreactiontozopiclonewithflumazenil |