Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine
Background: Herbal products encompass a wide range of natural substances that show great potential as therapeutic materials. Consequently, there has been a substantial investigation into the therapeutic potential of numerous plant species in recent times. The present study sought to determine the co...
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An-Najah National University
2024-10-01
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| Series: | مجلة جامعة النجاح للأبحاث العلوم الطبيعية |
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| Online Access: | https://journals.najah.edu/media/journals/full_texts/6_1drCzbO.pdf |
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| author | Belal M. Rahhal |
| author_facet | Belal M. Rahhal |
| author_sort | Belal M. Rahhal |
| collection | DOAJ |
| description | Background: Herbal products encompass a wide range of natural substances that show great potential as therapeutic materials. Consequently, there has been a substantial investigation into the therapeutic potential of numerous plant species in recent times. The present study sought to determine the components and assess the antioxidant, antilipase, α-amylase, and α-glycosidase enzyme inhibitory activities of Stiefia multicaulis (Vahl) Soják Vahl hexane, acetone, methanol, and aqueous fractions. Methods: Standard pharmacopeia methods were used to conduct screenings for both quantitative and qualitative phytoconstituents. The lipase, α-amylase, and α-glycosidase enzyme inhibitory activities were assessed using established reference methods. In addition, the antioxidant activity was assessed using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Results: The screening methods of pharmacopeias revealed that S. multicaulis contains a wide range of secondary metabolites, especially tannins. However, the most potent antioxidant, antilipase, α-glucosidase, and α-amylase inhibitory activities were acetone fraction, hexane, methanol, and aqueous S. multicaulis fractions, respectively. Conclusion: The current study outcomes are the first on the α-amylase, lipase, α-glucosidase inhibitory activities of S. multicaulis four solvent fractions. Further investigations are needed to assess the in vivo potential of these plant fractions in animal models. |
| format | Article |
| id | doaj-art-1701970a2d4a4f1e8adb1a765e37b2bc |
| institution | Kabale University |
| issn | 1727-2114 2311-8865 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | An-Najah National University |
| record_format | Article |
| series | مجلة جامعة النجاح للأبحاث العلوم الطبيعية |
| spelling | doaj-art-1701970a2d4a4f1e8adb1a765e37b2bc2025-08-20T04:00:44ZengAn-Najah National Universityمجلة جامعة النجاح للأبحاث العلوم الطبيعية1727-21142311-88652024-10-01391475410.35552/anujr.a.39.1.2266Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in PalestineBelal M. Rahhal0Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.Background: Herbal products encompass a wide range of natural substances that show great potential as therapeutic materials. Consequently, there has been a substantial investigation into the therapeutic potential of numerous plant species in recent times. The present study sought to determine the components and assess the antioxidant, antilipase, α-amylase, and α-glycosidase enzyme inhibitory activities of Stiefia multicaulis (Vahl) Soják Vahl hexane, acetone, methanol, and aqueous fractions. Methods: Standard pharmacopeia methods were used to conduct screenings for both quantitative and qualitative phytoconstituents. The lipase, α-amylase, and α-glycosidase enzyme inhibitory activities were assessed using established reference methods. In addition, the antioxidant activity was assessed using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Results: The screening methods of pharmacopeias revealed that S. multicaulis contains a wide range of secondary metabolites, especially tannins. However, the most potent antioxidant, antilipase, α-glucosidase, and α-amylase inhibitory activities were acetone fraction, hexane, methanol, and aqueous S. multicaulis fractions, respectively. Conclusion: The current study outcomes are the first on the α-amylase, lipase, α-glucosidase inhibitory activities of S. multicaulis four solvent fractions. Further investigations are needed to assess the in vivo potential of these plant fractions in animal models.https://journals.najah.edu/media/journals/full_texts/6_1drCzbO.pdfantioxidant;α-amylaseα-glucosidase;multicaulis;antilipase;stiefia |
| spellingShingle | Belal M. Rahhal Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine مجلة جامعة النجاح للأبحاث العلوم الطبيعية antioxidant; α-amylase α-glucosidase; multicaulis; antilipase; stiefia |
| title | Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine |
| title_full | Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine |
| title_fullStr | Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine |
| title_full_unstemmed | Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine |
| title_short | Chemical composition and physiological bioactivities of Stiefia multicaulis (Vahl) Soják Vahl grown in Palestine |
| title_sort | chemical composition and physiological bioactivities of stiefia multicaulis vahl sojak vahl grown in palestine |
| topic | antioxidant; α-amylase α-glucosidase; multicaulis; antilipase; stiefia |
| url | https://journals.najah.edu/media/journals/full_texts/6_1drCzbO.pdf |
| work_keys_str_mv | AT belalmrahhal chemicalcompositionandphysiologicalbioactivitiesofstiefiamulticaulisvahlsojakvahlgrowninpalestine |