Lipopolysaccharide-induced changes in the hepatic transcriptome revealed breed-specific response in St. Croix and Suffolk sheep

Lipopolysaccharide-induced changes in the hepatic transcriptome revealed breed-specific response in St. Croix and Suffolk sheep

This study aimed to investigate breed-specific differences in the liver transcriptomic response to lipopolysaccharide (LPS) in St. Croix (STC) and Suffolk (SUF) sheep. A total of 18 sheep (9 STC and 9 SUF) were administered LPS (E. coli O111), at a dosage of 2.5 mg/kg via I.V. After euthanasia, live...

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Bibliographic Details
Main Authors: Samanthia R. Johnson, Kelsey L. Bentley, Scott A. Bowdridge, Ibukun M. Ogunade
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Animal Science
Subjects:
transcriptome
LPS
inflammatory
DEGs
response
Online Access:https://www.frontiersin.org/articles/10.3389/fanim.2025.1565253/full
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