Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were prese...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/615213 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558294300884992 |
|---|---|
| author | Liwen Huang Xinghuai Sun Gang Luo Shuai Liu Rui Liu Behzad Mansouri Vicky wing lai Wong Wen Wen Hong Liu Ai-Hou Wang |
| author_facet | Liwen Huang Xinghuai Sun Gang Luo Shuai Liu Rui Liu Behzad Mansouri Vicky wing lai Wong Wen Wen Hong Liu Ai-Hou Wang |
| author_sort | Liwen Huang |
| collection | DOAJ |
| description | Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were presented anaglyphically on a computer screen. A square target resembling Landolt C had 2 openings, one in red and one in cyan color. Through blue-red goggles, each eye could only see one of the two openings. The patient was required to report the location of the opening presented to the amblyopic eye. It started at an opening size of 800 sec of arc, went up and down in 160 sec of arc step, and stopped when reaching the 5th reversals. Ten patients with anisometropic amblyopia older than age 14 (average age: 26.7) were recruited and received ISVA treatment for 6 weeks, with 2 training sessions per day. Results. Both Titmus stereopsis (z=-2.809, P=0.005) and Random-dot stereopsis (z=-2.317, P=0.018) were significantly improved. Average improvement in best corrected visual acuity (BCVA) was 0.74 line (t=5.842, P<0.001). Conclusions. The ISVA treatment may be effective in treating amblyopia and restoring stereoscopic function. |
| format | Article |
| id | doaj-art-16ebca70ed574a7f98250be4b68adad2 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-16ebca70ed574a7f98250be4b68adad22025-02-03T01:32:43ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/615213615213Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel ApproachLiwen Huang0Xinghuai Sun1Gang Luo2Shuai Liu3Rui Liu4Behzad Mansouri5Vicky wing lai Wong6Wen Wen7Hong Liu8Ai-Hou Wang9Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaSchepens Eye Research Institute, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02135, USADepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Internal Medicine, Section of Neurology, Room GF328, Health Sciences Centre, University of Manitoba, 820 Sherbrook Street, Winnipeg MB, R3T 2N2, CanadaDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 FenYang Road, Shanghai 200031, ChinaDepartment of Ophthalmology, National Taiwan University Hospital, 7 ZhongShan S Road, Taipei 10002, TaiwanAims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were presented anaglyphically on a computer screen. A square target resembling Landolt C had 2 openings, one in red and one in cyan color. Through blue-red goggles, each eye could only see one of the two openings. The patient was required to report the location of the opening presented to the amblyopic eye. It started at an opening size of 800 sec of arc, went up and down in 160 sec of arc step, and stopped when reaching the 5th reversals. Ten patients with anisometropic amblyopia older than age 14 (average age: 26.7) were recruited and received ISVA treatment for 6 weeks, with 2 training sessions per day. Results. Both Titmus stereopsis (z=-2.809, P=0.005) and Random-dot stereopsis (z=-2.317, P=0.018) were significantly improved. Average improvement in best corrected visual acuity (BCVA) was 0.74 line (t=5.842, P<0.001). Conclusions. The ISVA treatment may be effective in treating amblyopia and restoring stereoscopic function.http://dx.doi.org/10.1155/2014/615213 |
| spellingShingle | Liwen Huang Xinghuai Sun Gang Luo Shuai Liu Rui Liu Behzad Mansouri Vicky wing lai Wong Wen Wen Hong Liu Ai-Hou Wang Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach Journal of Ophthalmology |
| title | Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach |
| title_full | Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach |
| title_fullStr | Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach |
| title_full_unstemmed | Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach |
| title_short | Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach |
| title_sort | interocular shift of visual attention enhances stereopsis and visual acuities of anisometropic amblyopes beyond the critical period of visual development a novel approach |
| url | http://dx.doi.org/10.1155/2014/615213 |
| work_keys_str_mv | AT liwenhuang interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT xinghuaisun interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT gangluo interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT shuailiu interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT ruiliu interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT behzadmansouri interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT vickywinglaiwong interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT wenwen interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT hongliu interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach AT aihouwang interocularshiftofvisualattentionenhancesstereopsisandvisualacuitiesofanisometropicamblyopesbeyondthecriticalperiodofvisualdevelopmentanovelapproach |