Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study

Objectives. In Japan, caudal block with 1% lidocaine is commonly used for transrectal prostate biopsy. Although 10 mL of 1% lidocaine is commonly used, the appropriate dosage of 1% lidocaine has not been studied. Our hospital routinely uses two different doses (5 or 10 mL) of 1% lidocaine for caudal...

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Main Authors: Norichika Ueda, Mototaka Sato, Shunsuke Mori, Atsuki Matsukawa, Yuta Oki, Yuma Kujime, Ryoya Mizuno, Hiromu Horitani, Tetsuya Yamamoto, Shota Fukae, Mitsuhiro Yoshinaga, Makoto Matsushita, Mai Akiyama, Satoshi Kamido, Ayako Honda, Jiro Nakayama, Norihide Tei, Osamu Miyake
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2024/9331738
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author Norichika Ueda
Mototaka Sato
Shunsuke Mori
Atsuki Matsukawa
Yuta Oki
Yuma Kujime
Ryoya Mizuno
Hiromu Horitani
Tetsuya Yamamoto
Shota Fukae
Mitsuhiro Yoshinaga
Makoto Matsushita
Mai Akiyama
Satoshi Kamido
Ayako Honda
Jiro Nakayama
Norihide Tei
Osamu Miyake
author_facet Norichika Ueda
Mototaka Sato
Shunsuke Mori
Atsuki Matsukawa
Yuta Oki
Yuma Kujime
Ryoya Mizuno
Hiromu Horitani
Tetsuya Yamamoto
Shota Fukae
Mitsuhiro Yoshinaga
Makoto Matsushita
Mai Akiyama
Satoshi Kamido
Ayako Honda
Jiro Nakayama
Norihide Tei
Osamu Miyake
author_sort Norichika Ueda
collection DOAJ
description Objectives. In Japan, caudal block with 1% lidocaine is commonly used for transrectal prostate biopsy. Although 10 mL of 1% lidocaine is commonly used, the appropriate dosage of 1% lidocaine has not been studied. Our hospital routinely uses two different doses (5 or 10 mL) of 1% lidocaine for caudal block for transrectal prostate biopsy. Herein, we retrospectively evaluated the efficacy and safety of both doses of 1% lidocaine. Methods. This retrospective study included 869 patients who underwent transrectal prostate biopsy with caudal block at our hospital. The amount of 1% lidocaine was determined by the day of the week on which the biopsy was performed, and the patient voluntarily chose the day of the biopsy, unaware of the dose of 1% lidocaine used on that day. Pain, anal sphincter tonus, cancer diagnosis rate, and early complications were compared. Results. In total, 466 and 403 patients received 5 and 10 mL of 1% lidocaine for a caudal block, respectively. After propensity-score matching for patient characteristics, each group contained 395 patients. The pain score, anal sphincter tonus score, or prostate cancer diagnosis rate were not significantly different between the two groups. However, rectal bleeding was significantly more frequent and severe in the 10-mL than the 5-mL group (p=0.018 and p=0.0036, respectively). The incidence of other complications was not significantly different between the groups. Conclusions. Our results suggest that 5 mL of 1% lidocaine may be more suitable than 10 mL for caudal block during transrectal prostate biopsy.
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spelling doaj-art-16e88c1f322a4a3aa3b2077459fe2ef52025-02-03T07:23:43ZengWileyAdvances in Urology1687-63772024-01-01202410.1155/2024/9331738Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort StudyNorichika Ueda0Mototaka Sato1Shunsuke Mori2Atsuki Matsukawa3Yuta Oki4Yuma Kujime5Ryoya Mizuno6Hiromu Horitani7Tetsuya Yamamoto8Shota Fukae9Mitsuhiro Yoshinaga10Makoto Matsushita11Mai Akiyama12Satoshi Kamido13Ayako Honda14Jiro Nakayama15Norihide Tei16Osamu Miyake17Department of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyPharmaceuticals and Medical Devices AgencyDepartment of AnesthesiologyDepartment of UrologyDepartment of UrologyDepartment of UrologyObjectives. In Japan, caudal block with 1% lidocaine is commonly used for transrectal prostate biopsy. Although 10 mL of 1% lidocaine is commonly used, the appropriate dosage of 1% lidocaine has not been studied. Our hospital routinely uses two different doses (5 or 10 mL) of 1% lidocaine for caudal block for transrectal prostate biopsy. Herein, we retrospectively evaluated the efficacy and safety of both doses of 1% lidocaine. Methods. This retrospective study included 869 patients who underwent transrectal prostate biopsy with caudal block at our hospital. The amount of 1% lidocaine was determined by the day of the week on which the biopsy was performed, and the patient voluntarily chose the day of the biopsy, unaware of the dose of 1% lidocaine used on that day. Pain, anal sphincter tonus, cancer diagnosis rate, and early complications were compared. Results. In total, 466 and 403 patients received 5 and 10 mL of 1% lidocaine for a caudal block, respectively. After propensity-score matching for patient characteristics, each group contained 395 patients. The pain score, anal sphincter tonus score, or prostate cancer diagnosis rate were not significantly different between the two groups. However, rectal bleeding was significantly more frequent and severe in the 10-mL than the 5-mL group (p=0.018 and p=0.0036, respectively). The incidence of other complications was not significantly different between the groups. Conclusions. Our results suggest that 5 mL of 1% lidocaine may be more suitable than 10 mL for caudal block during transrectal prostate biopsy.http://dx.doi.org/10.1155/2024/9331738
spellingShingle Norichika Ueda
Mototaka Sato
Shunsuke Mori
Atsuki Matsukawa
Yuta Oki
Yuma Kujime
Ryoya Mizuno
Hiromu Horitani
Tetsuya Yamamoto
Shota Fukae
Mitsuhiro Yoshinaga
Makoto Matsushita
Mai Akiyama
Satoshi Kamido
Ayako Honda
Jiro Nakayama
Norihide Tei
Osamu Miyake
Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
Advances in Urology
title Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
title_full Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
title_fullStr Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
title_full_unstemmed Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
title_short Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study
title_sort lower dose of 5 ml of 1 lidocaine is more suitable than the conventional 10 ml for caudal block in transrectal prostate biopsy a retrospective cohort study
url http://dx.doi.org/10.1155/2024/9331738
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