Geohelminths: public health significance

The worldwide prevalence of geohelminths and their unique place in evolutionary biology have attracted research focus. These major soil-transmitted intestinal nematodes that cause human diseases are the nematode roundworm (Ascaris lumbricoides), the whipworm (Trichuris trichiura) and the two hookwor...

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Main Authors: Suvash Chandra Ojha, Chayannan Jaide, Natini Jinawath, Porpon Rotjanapan, Pankaj Baral
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2014-01-01
Series:Journal of Infection in Developing Countries
Subjects:
Online Access:https://jidc.org/index.php/journal/article/view/3183
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author Suvash Chandra Ojha
Chayannan Jaide
Natini Jinawath
Porpon Rotjanapan
Pankaj Baral
author_facet Suvash Chandra Ojha
Chayannan Jaide
Natini Jinawath
Porpon Rotjanapan
Pankaj Baral
author_sort Suvash Chandra Ojha
collection DOAJ
description The worldwide prevalence of geohelminths and their unique place in evolutionary biology have attracted research focus. These major soil-transmitted intestinal nematodes that cause human diseases are the nematode roundworm (Ascaris lumbricoides), the whipworm (Trichuris trichiura) and the two hookworms (Ancylostoma duodenale and Necator americanus), often collectively referred as geohelminths. Studies of geohelminthiasis in poorly nourished children in developing regions report that geohelminths contribute to stunted growth and cognitive impairment. Insights into immunology have shed light on the modulatory role of the parasite on the host immune system and have defined the role of T cells in controlling geohelminthic infection. Recent molecular biological techniques have created an opportunity to analyse the interaction between parasites and their hosts at the molecular level. This paper is a review of the recent literature that examined the prevalence of geohelminthiasis in developing countries, the association between geohelminths in relation to public health, parasitological/diagnostic features, and therapeutic and preventive aspects of these major soil-transmitted helminth (STH) pathogens in humans.
format Article
id doaj-art-16e1ce4e8a5e451a8eff7b5c1fdf8cca
institution OA Journals
issn 1972-2680
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publishDate 2014-01-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-16e1ce4e8a5e451a8eff7b5c1fdf8cca2025-08-20T02:27:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802014-01-0180110.3855/jidc.3183Geohelminths: public health significanceSuvash Chandra Ojha0Chayannan Jaide1Natini Jinawath2Porpon Rotjanapan3Pankaj Baral4Mahidol University, Bangkok, ThailandMahidol University, Bangkok, ThailandMahidol University, Bangkok, ThailandMahidol University, Bangkok, ThailandMahidol University, Bangkok, ThailandThe worldwide prevalence of geohelminths and their unique place in evolutionary biology have attracted research focus. These major soil-transmitted intestinal nematodes that cause human diseases are the nematode roundworm (Ascaris lumbricoides), the whipworm (Trichuris trichiura) and the two hookworms (Ancylostoma duodenale and Necator americanus), often collectively referred as geohelminths. Studies of geohelminthiasis in poorly nourished children in developing regions report that geohelminths contribute to stunted growth and cognitive impairment. Insights into immunology have shed light on the modulatory role of the parasite on the host immune system and have defined the role of T cells in controlling geohelminthic infection. Recent molecular biological techniques have created an opportunity to analyse the interaction between parasites and their hosts at the molecular level. This paper is a review of the recent literature that examined the prevalence of geohelminthiasis in developing countries, the association between geohelminths in relation to public health, parasitological/diagnostic features, and therapeutic and preventive aspects of these major soil-transmitted helminth (STH) pathogens in humans. https://jidc.org/index.php/journal/article/view/3183geohelminthsimmune responsepathogenesisprevalencetreatmentnematodes
spellingShingle Suvash Chandra Ojha
Chayannan Jaide
Natini Jinawath
Porpon Rotjanapan
Pankaj Baral
Geohelminths: public health significance
Journal of Infection in Developing Countries
geohelminths
immune response
pathogenesis
prevalence
treatment
nematodes
title Geohelminths: public health significance
title_full Geohelminths: public health significance
title_fullStr Geohelminths: public health significance
title_full_unstemmed Geohelminths: public health significance
title_short Geohelminths: public health significance
title_sort geohelminths public health significance
topic geohelminths
immune response
pathogenesis
prevalence
treatment
nematodes
url https://jidc.org/index.php/journal/article/view/3183
work_keys_str_mv AT suvashchandraojha geohelminthspublichealthsignificance
AT chayannanjaide geohelminthspublichealthsignificance
AT natinijinawath geohelminthspublichealthsignificance
AT porponrotjanapan geohelminthspublichealthsignificance
AT pankajbaral geohelminthspublichealthsignificance