Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions

Fe(OTs)3·6H2O, a water-tolerant Lewis acid catalyst for electrophilic substitution of aldehydes with indole, produces bis(indolyl)methane through an environment-friendly and green procedure. With its low sensitivity to oxygen, great tolerance to diverse functional groups, green reaction media, and o...

Full description

Saved in:
Bibliographic Details
Main Authors: Akanksha Mishra, Mrinal Talukdar, Alpa Y. Dave, Eeshwaraiah Begari
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624007082
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832583069061611520
author Akanksha Mishra
Mrinal Talukdar
Alpa Y. Dave
Eeshwaraiah Begari
author_facet Akanksha Mishra
Mrinal Talukdar
Alpa Y. Dave
Eeshwaraiah Begari
author_sort Akanksha Mishra
collection DOAJ
description Fe(OTs)3·6H2O, a water-tolerant Lewis acid catalyst for electrophilic substitution of aldehydes with indole, produces bis(indolyl)methane through an environment-friendly and green procedure. With its low sensitivity to oxygen, great tolerance to diverse functional groups, green reaction media, and outstanding yields, this procedure is an effective method for synthesizing bis(indolyl)methane under relatively benign circumstances, making it suited for both laboratory and industrial use.
format Article
id doaj-art-167ab0e6df0841639dc68297a8bb9ed5
institution Kabale University
issn 2211-7156
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Results in Chemistry
spelling doaj-art-167ab0e6df0841639dc68297a8bb9ed52025-01-29T05:00:56ZengElsevierResults in Chemistry2211-71562025-01-0113102012Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditionsAkanksha Mishra0Mrinal Talukdar1Alpa Y. Dave2Eeshwaraiah Begari3School of Applied Material Sciences, Centre for Applied Chemistry, Central University of Gujarat, Gandhinagar 382030, IndiaSchool of Applied Material Sciences, Centre for Applied Chemistry, Central University of Gujarat, Gandhinagar 382030, IndiaSchool of Applied Material Sciences, Centre for Applied Chemistry, Central University of Gujarat, Gandhinagar 382030, IndiaCorresponding author.; School of Applied Material Sciences, Centre for Applied Chemistry, Central University of Gujarat, Gandhinagar 382030, IndiaFe(OTs)3·6H2O, a water-tolerant Lewis acid catalyst for electrophilic substitution of aldehydes with indole, produces bis(indolyl)methane through an environment-friendly and green procedure. With its low sensitivity to oxygen, great tolerance to diverse functional groups, green reaction media, and outstanding yields, this procedure is an effective method for synthesizing bis(indolyl)methane under relatively benign circumstances, making it suited for both laboratory and industrial use.http://www.sciencedirect.com/science/article/pii/S2211715624007082water-tolerant Lewis acid catalystElectrophilic substitutionAldehydeIndoleGreen protocol
spellingShingle Akanksha Mishra
Mrinal Talukdar
Alpa Y. Dave
Eeshwaraiah Begari
Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
Results in Chemistry
water-tolerant Lewis acid catalyst
Electrophilic substitution
Aldehyde
Indole
Green protocol
title Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
title_full Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
title_fullStr Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
title_full_unstemmed Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
title_short Iron(III) tosylate hexahydrate (Fe(OTs)3⋅ 6H2O), a green Water-Tolerant Lewis acid catalyst for the synthesis of Bis(indolyl)methanes in benign conditions
title_sort iron iii tosylate hexahydrate fe ots 3⋅ 6h2o a green water tolerant lewis acid catalyst for the synthesis of bis indolyl methanes in benign conditions
topic water-tolerant Lewis acid catalyst
Electrophilic substitution
Aldehyde
Indole
Green protocol
url http://www.sciencedirect.com/science/article/pii/S2211715624007082
work_keys_str_mv AT akankshamishra ironiiitosylatehexahydratefeots36h2oagreenwatertolerantlewisacidcatalystforthesynthesisofbisindolylmethanesinbenignconditions
AT mrinaltalukdar ironiiitosylatehexahydratefeots36h2oagreenwatertolerantlewisacidcatalystforthesynthesisofbisindolylmethanesinbenignconditions
AT alpaydave ironiiitosylatehexahydratefeots36h2oagreenwatertolerantlewisacidcatalystforthesynthesisofbisindolylmethanesinbenignconditions
AT eeshwaraiahbegari ironiiitosylatehexahydratefeots36h2oagreenwatertolerantlewisacidcatalystforthesynthesisofbisindolylmethanesinbenignconditions