Ontogeny of Toll-like receptor mediated cytokine responses of South African infants throughout the first year of life.

Ontogeny of Toll-like receptor mediated cytokine responses of South African infants throughout the first year of life.

The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased risk for infection as well as a suboptimal response to vaccination in early li...

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Main Authors: Brian A Reikie, Rozanne C M Adams, Candice E Ruck, Kevin Ho, Aleksandra Leligdowicz, Santoshan Pillay, Shalena Naidoo, Edgardo S Fortuno, Corena de Beer, Wolfgang Preiser, Mark F Cotton, David P Speert, Monika Esser, Tobias R Kollmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0044763&type=printable
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