FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner
Background Acute kidney injury (AKI) is a frequent complication of severe acute pancreatitis (SAP). Previous investigations have revealed the involvement of FTO alpha-ketoglutarate-dependent dioxygenase (FTO) and aquaporin 3 (AQP3) in AKI. Therefore, the aim of this study is to explore the associati...
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Main Authors: | Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Renal Failure |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2322037 |
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