Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges

Squamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthom...

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Main Authors: Attila Vass, Gábor Vass, Erika Gabriella Kis, Levente Kuthi, Judit Oláh, Tibor Hortobágyi, Edit Tóth-Molnár
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2019/5830493
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author Attila Vass
Gábor Vass
Erika Gabriella Kis
Levente Kuthi
Judit Oláh
Tibor Hortobágyi
Edit Tóth-Molnár
author_facet Attila Vass
Gábor Vass
Erika Gabriella Kis
Levente Kuthi
Judit Oláh
Tibor Hortobágyi
Edit Tóth-Molnár
author_sort Attila Vass
collection DOAJ
description Squamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthoma, inverted follicular keratosis, and squamous cell carcinoma; however, these lesions are not associated with HPV infection. The authors present a female patient who noticed an extremely rapidly growing tumor destructing the left lower eyelid. The histological analysis of the biopsy sample revealed a virus-induced squamoproliferative lesion. The eyelid affected was completely removed, and the histological examination resulted in a HPV induced endophytic squamous cell papilloma. The tarsus and the conjunctiva were replaced by a chondromucosal graft harvested from the nasal septum, while the skin defect could be closed directly. Restoration of the eyelid function has been achieved with satisfying functional and cosmetic results.
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publisher Wiley
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-163a9bcd4f24483a95465f438248905c2025-02-03T01:23:44ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302019-01-01201910.1155/2019/58304935830493Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic ChallengesAttila Vass0Gábor Vass1Erika Gabriella Kis2Levente Kuthi3Judit Oláh4Tibor Hortobágyi5Edit Tóth-Molnár6Department of Ophthalmology, University of Szeged, Szeged, HungaryDepartment of Otolaryngology and Head and Neck Surgery, University of Szeged, Szeged, HungaryDepartment of Dermatology and Allergology, University of Szeged, Szeged, HungaryDepartment of Pathology, University of Szeged, Szeged, HungaryDepartment of Dermatology and Allergology, University of Szeged, Szeged, HungaryDepartment of Pathology, University of Szeged, Szeged, HungaryDepartment of Ophthalmology, University of Szeged, Szeged, HungarySquamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthoma, inverted follicular keratosis, and squamous cell carcinoma; however, these lesions are not associated with HPV infection. The authors present a female patient who noticed an extremely rapidly growing tumor destructing the left lower eyelid. The histological analysis of the biopsy sample revealed a virus-induced squamoproliferative lesion. The eyelid affected was completely removed, and the histological examination resulted in a HPV induced endophytic squamous cell papilloma. The tarsus and the conjunctiva were replaced by a chondromucosal graft harvested from the nasal septum, while the skin defect could be closed directly. Restoration of the eyelid function has been achieved with satisfying functional and cosmetic results.http://dx.doi.org/10.1155/2019/5830493
spellingShingle Attila Vass
Gábor Vass
Erika Gabriella Kis
Levente Kuthi
Judit Oláh
Tibor Hortobágyi
Edit Tóth-Molnár
Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
Case Reports in Ophthalmological Medicine
title Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
title_full Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
title_fullStr Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
title_full_unstemmed Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
title_short Giant Squamous Cell Papilloma of the Eyelid—Diagnostic and Therapeutic Challenges
title_sort giant squamous cell papilloma of the eyelid diagnostic and therapeutic challenges
url http://dx.doi.org/10.1155/2019/5830493
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