Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment
Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/4917968 |
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| author | Álvaro Bengoa-González Enrique Mencía-Gutiérrez Beatriz Alonso-Martín Bianca-Maria Laslău Elena Salvador Ana-Belén Enguita-Valls María-Dolores Lago-Llinás |
| author_facet | Álvaro Bengoa-González Enrique Mencía-Gutiérrez Beatriz Alonso-Martín Bianca-Maria Laslău Elena Salvador Ana-Belén Enguita-Valls María-Dolores Lago-Llinás |
| author_sort | Álvaro Bengoa-González |
| collection | DOAJ |
| description | Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence. |
| format | Article |
| id | doaj-art-162d455aff2f450f893123ed642aadb3 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-162d455aff2f450f893123ed642aadb32025-02-03T05:44:12ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/49179684917968Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and TreatmentÁlvaro Bengoa-González0Enrique Mencía-Gutiérrez1Beatriz Alonso-Martín2Bianca-Maria Laslău3Elena Salvador4Ana-Belén Enguita-Valls5María-Dolores Lago-Llinás6Ophthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainRadiology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPathology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainGiant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence.http://dx.doi.org/10.1155/2021/4917968 |
| spellingShingle | Álvaro Bengoa-González Enrique Mencía-Gutiérrez Beatriz Alonso-Martín Bianca-Maria Laslău Elena Salvador Ana-Belén Enguita-Valls María-Dolores Lago-Llinás Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment Case Reports in Ophthalmological Medicine |
| title | Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment |
| title_full | Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment |
| title_fullStr | Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment |
| title_full_unstemmed | Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment |
| title_short | Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment |
| title_sort | giant cell reparative granuloma of the orbit clinicopathological characteristics and treatment |
| url | http://dx.doi.org/10.1155/2021/4917968 |
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