Study of interaction between metal ions and quercetin
A displacement test based on the interaction between the flavonoid quercetin and an excess of metal chloride allows the determination of the binding constant for the reaction between quercetin and Ca2+, Mg2+ and Ni2+. The values obtained were 2.20 ± 1.77 × 103 for Ca2+, 1.37 ± 0.59 × 103 for Mg2+ an...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2018-09-01
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| Series: | Food Science and Human Wellness |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453018300120 |
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| author | Taiane Souza de Castilho Tatiane Brescovites Matias Keller Paulo Nicolini Jaqueline Nicolini |
| author_facet | Taiane Souza de Castilho Tatiane Brescovites Matias Keller Paulo Nicolini Jaqueline Nicolini |
| author_sort | Taiane Souza de Castilho |
| collection | DOAJ |
| description | A displacement test based on the interaction between the flavonoid quercetin and an excess of metal chloride allows the determination of the binding constant for the reaction between quercetin and Ca2+, Mg2+ and Ni2+. The values obtained were 2.20 ± 1.77 × 103 for Ca2+, 1.37 ± 0.59 × 103 for Mg2+ and 7.03 ± 1.04 × 104 for Ni2+, and all interactions showed type 1:1 stoichiometry, as determined by titration and by the method of continuous variations (Job’s method). The complexion effect was observed qualitatively through a colorimetric change in the medium (yellow → neon yellow) and spectroscopically through a bathochromic shift in the absorption band of quercetin in the presence of metals. This investigation serves as a tool for the development and testing of materials capable of capturing toxic metal ions or favoring the absorption of beneficial ions (in relation to the human metabolism) through the construction of efficient bioorganic systems. The results reported herein allow understanding of this detection system, indicating the following ascending order of the binding constants (Mg2+ < Ca2+ < Al3+ < Ni2+). Keywords: Binding constants, Quercetin, Antioxidant properties |
| format | Article |
| id | doaj-art-1629bd081d6d49e0bfa1798d13503a07 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-1629bd081d6d49e0bfa1798d13503a072025-02-03T05:39:03ZengTsinghua University PressFood Science and Human Wellness2213-45302018-09-0173215219Study of interaction between metal ions and quercetinTaiane Souza de Castilho0Tatiane Brescovites Matias1Keller Paulo Nicolini2Jaqueline Nicolini3Instituto Federal do Paraná – IFPR, Lacoppi – Laboratório de Corantes e Processos Pirolíticos, Departamento de Química, Palmas, PR, BrazilInstituto Federal do Paraná – IFPR, Lacoppi – Laboratório de Corantes e Processos Pirolíticos, Departamento de Química, Palmas, PR, BrazilInstituto Federal do Paraná – IFPR, Lacoppi – Laboratório de Corantes e Processos Pirolíticos, Departamento de Química, Palmas, PR, BrazilCorresponding author.; Instituto Federal do Paraná – IFPR, Lacoppi – Laboratório de Corantes e Processos Pirolíticos, Departamento de Química, Palmas, PR, BrazilA displacement test based on the interaction between the flavonoid quercetin and an excess of metal chloride allows the determination of the binding constant for the reaction between quercetin and Ca2+, Mg2+ and Ni2+. The values obtained were 2.20 ± 1.77 × 103 for Ca2+, 1.37 ± 0.59 × 103 for Mg2+ and 7.03 ± 1.04 × 104 for Ni2+, and all interactions showed type 1:1 stoichiometry, as determined by titration and by the method of continuous variations (Job’s method). The complexion effect was observed qualitatively through a colorimetric change in the medium (yellow → neon yellow) and spectroscopically through a bathochromic shift in the absorption band of quercetin in the presence of metals. This investigation serves as a tool for the development and testing of materials capable of capturing toxic metal ions or favoring the absorption of beneficial ions (in relation to the human metabolism) through the construction of efficient bioorganic systems. The results reported herein allow understanding of this detection system, indicating the following ascending order of the binding constants (Mg2+ < Ca2+ < Al3+ < Ni2+). Keywords: Binding constants, Quercetin, Antioxidant propertieshttp://www.sciencedirect.com/science/article/pii/S2213453018300120 |
| spellingShingle | Taiane Souza de Castilho Tatiane Brescovites Matias Keller Paulo Nicolini Jaqueline Nicolini Study of interaction between metal ions and quercetin Food Science and Human Wellness |
| title | Study of interaction between metal ions and quercetin |
| title_full | Study of interaction between metal ions and quercetin |
| title_fullStr | Study of interaction between metal ions and quercetin |
| title_full_unstemmed | Study of interaction between metal ions and quercetin |
| title_short | Study of interaction between metal ions and quercetin |
| title_sort | study of interaction between metal ions and quercetin |
| url | http://www.sciencedirect.com/science/article/pii/S2213453018300120 |
| work_keys_str_mv | AT taianesouzadecastilho studyofinteractionbetweenmetalionsandquercetin AT tatianebrescovitesmatias studyofinteractionbetweenmetalionsandquercetin AT kellerpaulonicolini studyofinteractionbetweenmetalionsandquercetin AT jaquelinenicolini studyofinteractionbetweenmetalionsandquercetin |