Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]

Background and objectives This is a protocol for a living systematic review and meta-analysis. This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.I.T.T. pr...

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Main Authors: Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel
Format: Article
Language:English
Published: F1000 Research Ltd 2025-01-01
Series:Open Research Europe
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Online Access:https://open-research-europe.ec.europa.eu/articles/4-202/v2
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author Claudia Volecker-Rehage
Uros Marusic
Bettina Wollesen
Antoine Langeard
Tamar Yellon
Anna Wunderlich
Vera Belkin
Guoping Qian
Eleftheria Giannouli
Zbigniew Ossowski
Rafael A. Bernades
Yael Netz
Rajesh Sighdel
author_facet Claudia Volecker-Rehage
Uros Marusic
Bettina Wollesen
Antoine Langeard
Tamar Yellon
Anna Wunderlich
Vera Belkin
Guoping Qian
Eleftheria Giannouli
Zbigniew Ossowski
Rafael A. Bernades
Yael Netz
Rajesh Sighdel
author_sort Claudia Volecker-Rehage
collection DOAJ
description Background and objectives This is a protocol for a living systematic review and meta-analysis. This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.I.T.T. principles (frequency, intensity, time, type) as well as the physical and health status of the participants as moderators to analyse the mechanisms for the positive benefits of exercise interventions. The main research questions are: Which exercise types are most beneficial for improving functional mobility in various populations of older adults? Which physical exercise characteristics in terms of frequency, intensity, time and duration will achieve the greatest benefit in terms of the defined outcomes, i.e, the functional mobility of older adults? Methods The systematic literature research according to PRISMA guidelines will search databases like MEDLINE, APA Psych-Info and Web of Science. Inclusion criteria are: healthy older people ≥ 50 years, randomized-controlled trials including exercise intervention and a walking or mobility assessments (eg., TUG, SPPB) as an outcome measure. A preliminary search revealed more than 33,000 hits that will be screened by pairs of independent reviewers. The results will be summarized according to the effects regarding functional mobility and potential dose-response relations via respective meta-analysis. Conclusion The systematic review will comprise the knowledge of the existing literature with regards to the effects of the physical activity interventions compared to an active or inactive control group. We will summarize the effects with respect to the F.I.T.T.. They provide a foundation for structuring an optimal exercise training program. If possible, we will also compare interventions from the different categories (eg. cardiovascular, resistance, motor-coordinative, multicomponent or mind-body exercise) as a network analysis and report the influence of moderator variables. Based on the results evidence-based guidelines following GRADE for physical exercise interventions to improve functional mobility in older adults will be provided.
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spelling doaj-art-1620d97e04854ea08f6b7ef5150173792025-01-28T01:00:00ZengF1000 Research LtdOpen Research Europe2732-51212025-01-01420770Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]Claudia Volecker-Rehage0Uros Marusic1https://orcid.org/0000-0002-7420-2137Bettina Wollesen2https://orcid.org/0000-0002-1082-9141Antoine Langeard3Tamar Yellon4Anna Wunderlich5Vera Belkin6Guoping Qian7https://orcid.org/0000-0002-0472-7130Eleftheria Giannouli8https://orcid.org/0000-0001-7762-1348Zbigniew Ossowski9https://orcid.org/0000-0002-3226-2430Rafael A. Bernades10https://orcid.org/0000-0003-2110-7483Yael Netz11Rajesh Sighdel12https://orcid.org/0000-0002-8686-8569Neuromotor Behavior and Exercise, University of Münster, Münster, GermanyInstitute for Kinesiology Research, Science and Research Centre Koper, Koper, SloveniaHuman Movement Science, Universitat Hamburg, Hamburg, Hamburg, 20148, GermanyCOMETE UMR-S 1075, GIP Cyceron, Université de Caen Normandie, INSERM, Normandie Université, GIP Cyceron, Caen, Normandie, France, Caen, Normandie, FranceHenrietta Szold Hadassah Hebrew University School of Nursing, University Jerusalem, Jerusalem, IsraelBiological Psychology and Neuroergonomics, Technische Universitat Berlin, Berlin, Berlin, GermanyNeuromotor Behavior and Exercise, University of Münster, Münster, GermanyFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdansk, PolandDepartment of Health Sciences and Technology, ETH Zurich, Zurich, SwitzerlandFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdansk, PolandCenter for Interdisciplinary Research in Health Sciences, Faculty of Health Sciences and Nurses, Universidade Catolica Portuguesa, Lisbon, PortugalWingate Campus, The Levinsky-Wingate Academic College, Netanya, IsraelDepartment of Health Sciences, Alma Mater Europaea University, Maribor, SloveniaBackground and objectives This is a protocol for a living systematic review and meta-analysis. This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.I.T.T. principles (frequency, intensity, time, type) as well as the physical and health status of the participants as moderators to analyse the mechanisms for the positive benefits of exercise interventions. The main research questions are: Which exercise types are most beneficial for improving functional mobility in various populations of older adults? Which physical exercise characteristics in terms of frequency, intensity, time and duration will achieve the greatest benefit in terms of the defined outcomes, i.e, the functional mobility of older adults? Methods The systematic literature research according to PRISMA guidelines will search databases like MEDLINE, APA Psych-Info and Web of Science. Inclusion criteria are: healthy older people ≥ 50 years, randomized-controlled trials including exercise intervention and a walking or mobility assessments (eg., TUG, SPPB) as an outcome measure. A preliminary search revealed more than 33,000 hits that will be screened by pairs of independent reviewers. The results will be summarized according to the effects regarding functional mobility and potential dose-response relations via respective meta-analysis. Conclusion The systematic review will comprise the knowledge of the existing literature with regards to the effects of the physical activity interventions compared to an active or inactive control group. We will summarize the effects with respect to the F.I.T.T.. They provide a foundation for structuring an optimal exercise training program. If possible, we will also compare interventions from the different categories (eg. cardiovascular, resistance, motor-coordinative, multicomponent or mind-body exercise) as a network analysis and report the influence of moderator variables. Based on the results evidence-based guidelines following GRADE for physical exercise interventions to improve functional mobility in older adults will be provided.https://open-research-europe.ec.europa.eu/articles/4-202/v2functional mobility older adults physical training interventions evidence-based exercise eng
spellingShingle Claudia Volecker-Rehage
Uros Marusic
Bettina Wollesen
Antoine Langeard
Tamar Yellon
Anna Wunderlich
Vera Belkin
Guoping Qian
Eleftheria Giannouli
Zbigniew Ossowski
Rafael A. Bernades
Yael Netz
Rajesh Sighdel
Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
Open Research Europe
functional mobility
older adults
physical training interventions
evidence-based exercise
eng
title Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
title_full Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
title_fullStr Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
title_full_unstemmed Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
title_short Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2 approved]
title_sort evidence based exercise recommendations to improve functional mobility in older adults a study protocol for living systematic review and meta analysis version 2 peer review 2 approved
topic functional mobility
older adults
physical training interventions
evidence-based exercise
eng
url https://open-research-europe.ec.europa.eu/articles/4-202/v2
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