Cell-based immunotherapies for solid tumors: advances, challenges, and future directions

Cell-based immunotherapies for solid tumors: advances, challenges, and future directions

Cell-based immunotherapies, including CAR-T, CAR-NK, and TCR-T therapies, represent a transformative approach to cancer treatment by offering precise targeting of tumor cells. Despite their success in hematologic malignancies, these therapies encounter significant challenges in treating solid tumors...

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Bibliographic Details
Main Authors: Ting Zhao, Jinping You, Congyue Wang, Bo Li, Yuhan Liu, Mingjia Shao, Wuyang Zhao, Chuang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
cell-based immunotherapy
CAR-T
CAR-NK
TCR-T
solid tumors
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1551583/full
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