Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation

Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation

Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. This study determined how senescent ECs communicate with monocytes, whether extracellular vesicles (EVs) released fr...

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Bibliographic Details
Main Authors: Sarvatit Patel, Kai Ellis, Corey A. Scipione, Jason E. Fish, Kathryn L. Howe
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aging
cardiovascular disease
endothelial senescence
endothelial-monocyte communication
extracellular vesicles
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1506360/full
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