Current Trends in Implantable Left Ventricular Assist Devices

The shortage of appropriate donor organs and the expanding pool of patients waiting for heart transplantation have led to growing interest in alternative strategies, particularly in mechanical circulatory support. Improved results and the increased applicability and durability with left ventricular...

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Main Authors: Jens Garbade, Hartmuth B. Bittner, Markus J. Barten, Friedrich-Wilhelm Mohr
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.4061/2011/290561
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author Jens Garbade
Hartmuth B. Bittner
Markus J. Barten
Friedrich-Wilhelm Mohr
author_facet Jens Garbade
Hartmuth B. Bittner
Markus J. Barten
Friedrich-Wilhelm Mohr
author_sort Jens Garbade
collection DOAJ
description The shortage of appropriate donor organs and the expanding pool of patients waiting for heart transplantation have led to growing interest in alternative strategies, particularly in mechanical circulatory support. Improved results and the increased applicability and durability with left ventricular assist devices (LVADs) have enhanced this treatment option available for end-stage heart failure patients. Moreover, outcome with newer pumps have evolved to destination therapy for such patients. Currently, results using nonpulsatile continuous flow pumps document the evolution in outcomes following destination therapy achieved subsequent to the landmark Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure Trial (REMATCH), as well as the outcome of pulsatile designed second-generation LVADs. This review describes the currently available types of LVADs, their clinical use and outcomes, and focuses on the patient selection process.
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issn 2090-0597
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series Cardiology Research and Practice
spelling doaj-art-15e113c5957443c9b2f580f3ed7c49092025-02-03T01:11:26ZengWileyCardiology Research and Practice2090-05972011-01-01201110.4061/2011/290561290561Current Trends in Implantable Left Ventricular Assist DevicesJens Garbade0Hartmuth B. Bittner1Markus J. Barten2Friedrich-Wilhelm Mohr3Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, GermanyDepartment of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, GermanyDepartment of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, GermanyDepartment of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, GermanyThe shortage of appropriate donor organs and the expanding pool of patients waiting for heart transplantation have led to growing interest in alternative strategies, particularly in mechanical circulatory support. Improved results and the increased applicability and durability with left ventricular assist devices (LVADs) have enhanced this treatment option available for end-stage heart failure patients. Moreover, outcome with newer pumps have evolved to destination therapy for such patients. Currently, results using nonpulsatile continuous flow pumps document the evolution in outcomes following destination therapy achieved subsequent to the landmark Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure Trial (REMATCH), as well as the outcome of pulsatile designed second-generation LVADs. This review describes the currently available types of LVADs, their clinical use and outcomes, and focuses on the patient selection process.http://dx.doi.org/10.4061/2011/290561
spellingShingle Jens Garbade
Hartmuth B. Bittner
Markus J. Barten
Friedrich-Wilhelm Mohr
Current Trends in Implantable Left Ventricular Assist Devices
Cardiology Research and Practice
title Current Trends in Implantable Left Ventricular Assist Devices
title_full Current Trends in Implantable Left Ventricular Assist Devices
title_fullStr Current Trends in Implantable Left Ventricular Assist Devices
title_full_unstemmed Current Trends in Implantable Left Ventricular Assist Devices
title_short Current Trends in Implantable Left Ventricular Assist Devices
title_sort current trends in implantable left ventricular assist devices
url http://dx.doi.org/10.4061/2011/290561
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AT friedrichwilhelmmohr currenttrendsinimplantableleftventricularassistdevices