Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen
58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/857539 |
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| _version_ | 1832545693825236992 |
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| author | Rocio C. Garcia-Santibanez Veenu Gill Stanley Yancovitz DeWitt Pyburn |
| author_facet | Rocio C. Garcia-Santibanez Veenu Gill Stanley Yancovitz DeWitt Pyburn |
| author_sort | Rocio C. Garcia-Santibanez |
| collection | DOAJ |
| description | 58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed antifungal therapy. Serum Cryptococcus antigen titer decreased. He had a full neurological recovery. |
| format | Article |
| id | doaj-art-15de29577eeb4574880aee8cd65c0145 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-15de29577eeb4574880aee8cd65c01452025-02-03T07:24:54ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/857539857539Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus AntigenRocio C. Garcia-Santibanez0Veenu Gill1Stanley Yancovitz2DeWitt Pyburn3Department of Neurology, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Infectious Diseases, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Infectious Diseases, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Neurology, Mount Sinai Beth Israel, New York, NY 10003, USA58-year-old man presented with headache, nausea, vomiting, and gait disturbance. Brain MRI showed meningeal enhancement and herniation. Serum Cryptococcus antigen was positive but spinal fluid antigen and cultures were negative. A cerebellar biopsy revealed nonencapsulated Cryptococcus. He completed antifungal therapy. Serum Cryptococcus antigen titer decreased. He had a full neurological recovery.http://dx.doi.org/10.1155/2015/857539 |
| spellingShingle | Rocio C. Garcia-Santibanez Veenu Gill Stanley Yancovitz DeWitt Pyburn Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen Case Reports in Infectious Diseases |
| title | Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen |
| title_full | Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen |
| title_fullStr | Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen |
| title_full_unstemmed | Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen |
| title_short | Neuroinvasive Cryptococcosis in an Immunocompetent Patient with a Negative Spinal Fluid Cryptococcus Antigen |
| title_sort | neuroinvasive cryptococcosis in an immunocompetent patient with a negative spinal fluid cryptococcus antigen |
| url | http://dx.doi.org/10.1155/2015/857539 |
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