In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key

Abstract Objective This study aimed to create a 3D-printed customized transfer key and evaluate the accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using the transfer key. Methods A 3D-printed transfer key was designed, combining facial and intraoral (I...

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Main Authors: Anh Ho-Quynh Nguyen, Nam Cong-Nhat Huynh, Oanh Ngoc-Hoang Nguyen, Nhat Dinh-Minh Nguyen, Hai Hoang Phan, Jong-Eun Kim, Gan Jin, Khanh Hung Nguyen, Hung Trong Hoang
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:BDJ Open
Online Access:https://doi.org/10.1038/s41405-025-00303-1
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author Anh Ho-Quynh Nguyen
Nam Cong-Nhat Huynh
Oanh Ngoc-Hoang Nguyen
Nhat Dinh-Minh Nguyen
Hai Hoang Phan
Jong-Eun Kim
Gan Jin
Khanh Hung Nguyen
Hung Trong Hoang
author_facet Anh Ho-Quynh Nguyen
Nam Cong-Nhat Huynh
Oanh Ngoc-Hoang Nguyen
Nhat Dinh-Minh Nguyen
Hai Hoang Phan
Jong-Eun Kim
Gan Jin
Khanh Hung Nguyen
Hung Trong Hoang
author_sort Anh Ho-Quynh Nguyen
collection DOAJ
description Abstract Objective This study aimed to create a 3D-printed customized transfer key and evaluate the accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using the transfer key. Methods A 3D-printed transfer key was designed, combining facial and intraoral (IOS) scans. The design included components that recorded the 3D upper and lower arch at centric occlusion. The virtual patient model image was generated in-vitro using a phantom head with soft tissue simulation. Accuracy was assessed by superimposing the 3D scans with reference CBCT images and analyzing trueness and precision using root mean square (RMS) deviations. Results The transfer key included an intra-oral part that acts as an anterior deprogrammer to record the relationship of two dental arches at centric occlusion (CO) and an extra-oral with a rotatable cross-shaped design with two arms for locating the facial midline and the two pupils connecting line. Superimposition demonstrated high trueness (RMS: 0.51 mm for the arch regions, 0.69 mm for the whole head region, 0.85 mm in the face region) and precision (RMS: 0.41 mm for the arch regions, 0.52 mm for the entire head, 0.63 mm in the face region) significantly (p < 0.05). Minimal deviations were observed in critical areas, including the tooth and lip position, indicating that the virtual patient model was closely aligned with the CBCT reference. The dental arches achieved the highest accuracy, while slight deviations were noted in the facial regions. Conclusions The 3D-printed customized transfer key effectively enhanced the virtual patient model’s accuracy, surpassing traditional trueness and precision methods. This novel approach offers a streamlined, patient-friendly solution for digital dental workflows.
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spelling doaj-art-15da54505d95463b83d331e91768dba02025-02-02T12:38:08ZengNature Publishing GroupBDJ Open2056-807X2025-01-0111111010.1038/s41405-025-00303-1In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer keyAnh Ho-Quynh Nguyen0Nam Cong-Nhat Huynh1Oanh Ngoc-Hoang Nguyen2Nhat Dinh-Minh Nguyen3Hai Hoang Phan4Jong-Eun Kim5Gan Jin6Khanh Hung Nguyen7Hung Trong Hoang8Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityDepartment of Prosthodontics, Yonsei University College of DentistryDepartment of Prosthodontics, Yonsei University College of DentistryFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityFaculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh CityAbstract Objective This study aimed to create a 3D-printed customized transfer key and evaluate the accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using the transfer key. Methods A 3D-printed transfer key was designed, combining facial and intraoral (IOS) scans. The design included components that recorded the 3D upper and lower arch at centric occlusion. The virtual patient model image was generated in-vitro using a phantom head with soft tissue simulation. Accuracy was assessed by superimposing the 3D scans with reference CBCT images and analyzing trueness and precision using root mean square (RMS) deviations. Results The transfer key included an intra-oral part that acts as an anterior deprogrammer to record the relationship of two dental arches at centric occlusion (CO) and an extra-oral with a rotatable cross-shaped design with two arms for locating the facial midline and the two pupils connecting line. Superimposition demonstrated high trueness (RMS: 0.51 mm for the arch regions, 0.69 mm for the whole head region, 0.85 mm in the face region) and precision (RMS: 0.41 mm for the arch regions, 0.52 mm for the entire head, 0.63 mm in the face region) significantly (p < 0.05). Minimal deviations were observed in critical areas, including the tooth and lip position, indicating that the virtual patient model was closely aligned with the CBCT reference. The dental arches achieved the highest accuracy, while slight deviations were noted in the facial regions. Conclusions The 3D-printed customized transfer key effectively enhanced the virtual patient model’s accuracy, surpassing traditional trueness and precision methods. This novel approach offers a streamlined, patient-friendly solution for digital dental workflows.https://doi.org/10.1038/s41405-025-00303-1
spellingShingle Anh Ho-Quynh Nguyen
Nam Cong-Nhat Huynh
Oanh Ngoc-Hoang Nguyen
Nhat Dinh-Minh Nguyen
Hai Hoang Phan
Jong-Eun Kim
Gan Jin
Khanh Hung Nguyen
Hung Trong Hoang
In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
BDJ Open
title In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
title_full In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
title_fullStr In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
title_full_unstemmed In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
title_short In-vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3D-printed customized transfer key
title_sort in vitro accuracy of the virtual patient model with maxillomandibular relationship at centric occlusion using 3d printed customized transfer key
url https://doi.org/10.1038/s41405-025-00303-1
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