Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients

Fluid challenges are considered the cornerstone of resuscitation in critically ill patients. However, clinical studies have demonstrated that only about 50% of hemodynamically unstable patients are volume responsive. Furthermore, increasing evidence suggests that excess fluid resuscitation is associ...

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Main Authors: Alexander Levitov, Paul E. Marik
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/819696
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author Alexander Levitov
Paul E. Marik
author_facet Alexander Levitov
Paul E. Marik
author_sort Alexander Levitov
collection DOAJ
description Fluid challenges are considered the cornerstone of resuscitation in critically ill patients. However, clinical studies have demonstrated that only about 50% of hemodynamically unstable patients are volume responsive. Furthermore, increasing evidence suggests that excess fluid resuscitation is associated with increased mortality. It therefore becomes vital to assess a patient's fluid responsiveness prior to embarking on fluid loading. Static pressure (CVP, PAOP) and echocardiographic (IVC diameter, LVEDA) parameters fails to predict volume responsiveness. However, a number of dynamic echocardiographic parameters which are based on changes in vena-caval dimensions or cardiac function induce by positive pressure ventilation or passive leg raising appear to be highly predictive of volume responsiveness.
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spelling doaj-art-15bef57175a642618eb6ef2fc27648e12025-02-03T01:13:09ZengWileyCardiology Research and Practice2090-80162090-05972012-01-01201210.1155/2012/819696819696Echocardiographic Assessment of Preload Responsiveness in Critically Ill PatientsAlexander Levitov0Paul E. Marik1Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USADivision of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USAFluid challenges are considered the cornerstone of resuscitation in critically ill patients. However, clinical studies have demonstrated that only about 50% of hemodynamically unstable patients are volume responsive. Furthermore, increasing evidence suggests that excess fluid resuscitation is associated with increased mortality. It therefore becomes vital to assess a patient's fluid responsiveness prior to embarking on fluid loading. Static pressure (CVP, PAOP) and echocardiographic (IVC diameter, LVEDA) parameters fails to predict volume responsiveness. However, a number of dynamic echocardiographic parameters which are based on changes in vena-caval dimensions or cardiac function induce by positive pressure ventilation or passive leg raising appear to be highly predictive of volume responsiveness.http://dx.doi.org/10.1155/2012/819696
spellingShingle Alexander Levitov
Paul E. Marik
Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
Cardiology Research and Practice
title Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
title_full Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
title_fullStr Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
title_full_unstemmed Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
title_short Echocardiographic Assessment of Preload Responsiveness in Critically Ill Patients
title_sort echocardiographic assessment of preload responsiveness in critically ill patients
url http://dx.doi.org/10.1155/2012/819696
work_keys_str_mv AT alexanderlevitov echocardiographicassessmentofpreloadresponsivenessincriticallyillpatients
AT paulemarik echocardiographicassessmentofpreloadresponsivenessincriticallyillpatients