Primary Hyperparathyroidism: An Overview

Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this pa...

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Main Authors: Jessica MacKenzie-Feder, Sandra Sirrs, Donald Anderson, Jibran Sharif, Aneal Khan
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2011/251410
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author Jessica MacKenzie-Feder
Sandra Sirrs
Donald Anderson
Jibran Sharif
Aneal Khan
author_facet Jessica MacKenzie-Feder
Sandra Sirrs
Donald Anderson
Jibran Sharif
Aneal Khan
author_sort Jessica MacKenzie-Feder
collection DOAJ
description Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.
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institution Kabale University
issn 1687-8337
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language English
publishDate 2011-01-01
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series International Journal of Endocrinology
spelling doaj-art-15bdf448a8a146aab4b33492a7ae01202025-02-03T01:03:15ZengWileyInternational Journal of Endocrinology1687-83371687-83452011-01-01201110.1155/2011/251410251410Primary Hyperparathyroidism: An OverviewJessica MacKenzie-Feder0Sandra Sirrs1Donald Anderson2Jibran Sharif3Aneal Khan4Division of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDivision of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDivision of Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDepartment of Family Medicine, University of Saskatchwan, Regina, SK, S4P 0W5, CanadaAlberta Children's Hospital, University of Calgary, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, CanadaPrimary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.http://dx.doi.org/10.1155/2011/251410
spellingShingle Jessica MacKenzie-Feder
Sandra Sirrs
Donald Anderson
Jibran Sharif
Aneal Khan
Primary Hyperparathyroidism: An Overview
International Journal of Endocrinology
title Primary Hyperparathyroidism: An Overview
title_full Primary Hyperparathyroidism: An Overview
title_fullStr Primary Hyperparathyroidism: An Overview
title_full_unstemmed Primary Hyperparathyroidism: An Overview
title_short Primary Hyperparathyroidism: An Overview
title_sort primary hyperparathyroidism an overview
url http://dx.doi.org/10.1155/2011/251410
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AT sandrasirrs primaryhyperparathyroidismanoverview
AT donaldanderson primaryhyperparathyroidismanoverview
AT jibransharif primaryhyperparathyroidismanoverview
AT anealkhan primaryhyperparathyroidismanoverview