Primary Hyperparathyroidism: An Overview
Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this pa...
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Format: | Article |
Language: | English |
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Wiley
2011-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2011/251410 |
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author | Jessica MacKenzie-Feder Sandra Sirrs Donald Anderson Jibran Sharif Aneal Khan |
author_facet | Jessica MacKenzie-Feder Sandra Sirrs Donald Anderson Jibran Sharif Aneal Khan |
author_sort | Jessica MacKenzie-Feder |
collection | DOAJ |
description | Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics. |
format | Article |
id | doaj-art-15bdf448a8a146aab4b33492a7ae0120 |
institution | Kabale University |
issn | 1687-8337 1687-8345 |
language | English |
publishDate | 2011-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Endocrinology |
spelling | doaj-art-15bdf448a8a146aab4b33492a7ae01202025-02-03T01:03:15ZengWileyInternational Journal of Endocrinology1687-83371687-83452011-01-01201110.1155/2011/251410251410Primary Hyperparathyroidism: An OverviewJessica MacKenzie-Feder0Sandra Sirrs1Donald Anderson2Jibran Sharif3Aneal Khan4Division of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDivision of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDivision of Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, BC, V5Z 1M9, CanadaDepartment of Family Medicine, University of Saskatchwan, Regina, SK, S4P 0W5, CanadaAlberta Children's Hospital, University of Calgary, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, CanadaPrimary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.http://dx.doi.org/10.1155/2011/251410 |
spellingShingle | Jessica MacKenzie-Feder Sandra Sirrs Donald Anderson Jibran Sharif Aneal Khan Primary Hyperparathyroidism: An Overview International Journal of Endocrinology |
title | Primary Hyperparathyroidism: An Overview |
title_full | Primary Hyperparathyroidism: An Overview |
title_fullStr | Primary Hyperparathyroidism: An Overview |
title_full_unstemmed | Primary Hyperparathyroidism: An Overview |
title_short | Primary Hyperparathyroidism: An Overview |
title_sort | primary hyperparathyroidism an overview |
url | http://dx.doi.org/10.1155/2011/251410 |
work_keys_str_mv | AT jessicamackenziefeder primaryhyperparathyroidismanoverview AT sandrasirrs primaryhyperparathyroidismanoverview AT donaldanderson primaryhyperparathyroidismanoverview AT jibransharif primaryhyperparathyroidismanoverview AT anealkhan primaryhyperparathyroidismanoverview |