The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002
The aim of this study was to determine the frequency of resistance to antibiotics of the most frequently isolated bacteria from blood cultures of hospitalized patients during the period 1997-2002. The resistance to antibiotics was determined by disk diffusion method according to National Committee f...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2004-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404391M.pdf |
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| author | Mirović Veljko Tomanović Branka Konstantinović Sonja |
| author_facet | Mirović Veljko Tomanović Branka Konstantinović Sonja |
| author_sort | Mirović Veljko |
| collection | DOAJ |
| description | The aim of this study was to determine the frequency of resistance to antibiotics of the most frequently isolated bacteria from blood cultures of hospitalized patients during the period 1997-2002. The resistance to antibiotics was determined by disk diffusion method according to National Committee for Clinical Laboratory Standards procedures. The majority of staphylococci isolates were resistant to methicillin, and the proportion of methicillin-resistant Staphylococcus aureus was stable (76.8-81.6%), during the follow-up period. None of the staphylococci isolates were resistant to vancomycin, but there was a very high incidence of high-level resistance of enterococci to aminoglycosides (47.2-72.2%). In 1998, only one strain among enterococci was resistant to vancomycin (Enterococcus faecium, VanA fenotype). Enterococcus spp isolates expressed variable frequency of resistance to ampicillin (15-40.1%) during the follow-up period. Among Enterobacteriaceae there were no isolates resistant to imipenem, but dramatic increase of the resistance to ceftriaxone was found from 35.9% in 1997 to 95.9% in 2002 (p<0.001). Extended spectrum beta-lactamases production was found in all the species of enterobacteria isolates. Resistance to imipenem was observed in Acinetobacter spp isolates in 2002 for the first time. Pseudomonas spp isolates expressed high and very variable resistance to all antibiotics tested during the follow-up period. |
| format | Article |
| id | doaj-art-15a20901c14d4792a2147dfd807fd3f3 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2004-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-15a20901c14d4792a2147dfd807fd3f32025-08-20T03:17:31ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502004-01-0161439139710.2298/VSP0404391MThe frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002Mirović VeljkoTomanović BrankaKonstantinović SonjaThe aim of this study was to determine the frequency of resistance to antibiotics of the most frequently isolated bacteria from blood cultures of hospitalized patients during the period 1997-2002. The resistance to antibiotics was determined by disk diffusion method according to National Committee for Clinical Laboratory Standards procedures. The majority of staphylococci isolates were resistant to methicillin, and the proportion of methicillin-resistant Staphylococcus aureus was stable (76.8-81.6%), during the follow-up period. None of the staphylococci isolates were resistant to vancomycin, but there was a very high incidence of high-level resistance of enterococci to aminoglycosides (47.2-72.2%). In 1998, only one strain among enterococci was resistant to vancomycin (Enterococcus faecium, VanA fenotype). Enterococcus spp isolates expressed variable frequency of resistance to ampicillin (15-40.1%) during the follow-up period. Among Enterobacteriaceae there were no isolates resistant to imipenem, but dramatic increase of the resistance to ceftriaxone was found from 35.9% in 1997 to 95.9% in 2002 (p<0.001). Extended spectrum beta-lactamases production was found in all the species of enterobacteria isolates. Resistance to imipenem was observed in Acinetobacter spp isolates in 2002 for the first time. Pseudomonas spp isolates expressed high and very variable resistance to all antibiotics tested during the follow-up period.http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404391M.pdfbacteriological techniquesblooddrug resistancebacterialanti-bacterial agents |
| spellingShingle | Mirović Veljko Tomanović Branka Konstantinović Sonja The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 Vojnosanitetski Pregled bacteriological techniques blood drug resistance bacterial anti-bacterial agents |
| title | The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 |
| title_full | The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 |
| title_fullStr | The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 |
| title_full_unstemmed | The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 |
| title_short | The frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997-2002 |
| title_sort | frequency of resistance to antibiotics of most frequently isolated bacteria from blood cultures during the period 1997 2002 |
| topic | bacteriological techniques blood drug resistance bacterial anti-bacterial agents |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404391M.pdf |
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