Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure
Abstract Background The indicators of abdominal obesity have shown to be associated with a high risk of cardiovascular diseases (CVDs), even adjusted for body mass index (BMI). We aimed to investigate the association between neck circumference, waist-to-height ratio (WHtR), Chinese visceral adiposit...
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2024-11-01
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| Online Access: | https://doi.org/10.1186/s12937-024-01048-7 |
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| author | Zhijun Wu Zhe Huang Liang Sun Yuang Fu Shuohua Chen Shouling Wu Xiang Gao |
| author_facet | Zhijun Wu Zhe Huang Liang Sun Yuang Fu Shuohua Chen Shouling Wu Xiang Gao |
| author_sort | Zhijun Wu |
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| description | Abstract Background The indicators of abdominal obesity have shown to be associated with a high risk of cardiovascular diseases (CVDs), even adjusted for body mass index (BMI). We aimed to investigate the association between neck circumference, waist-to-height ratio (WHtR), Chinese visceral adiposity index (CVAI) and incident heart failure (HF) in Chinese adults. Methods The current study included 86,546 participants from two independent cohorts: the Kailuan I study established in 2006 and the Kailuan study II established in 2008. Participants aged 18–80 years who were free of CVDs or cancer were recruited at baseline. The values of neck circumference, WHtR and CVAI were available in 2014. The trajectory analysis was conducted using repeated measures of WHtR and CVAI in the 2008, 2010, 2012 and 2014 surveys. The incident HF cases were identified via reviewing medical records by cardiologists. Results During a mean follow-up of 5.62 years, 724 incident HF cases were documented. The highest quartiles of neck circumference, WHtR and CVAI respectively, were significantly associated with a high risk of HF compared to the lowest quartiles of adiposity measures (neck circumference: HR:1.30, 95%CI: 1.03–1.65; WHtR: HR:1.49, 95%CI: 1.16–1.92; and CVAI: HR:1.98, 95%CI: 1.48–2.65). The combination of adiposity measures with BMI or metabolic abnormalities jointly predicted incident HF. Presence of hypertension and diabetes appeared to be the major mediators, accounting for ∼ 8.11–24.7% of the associations between three indicators of abdominal obesity and HF risk. Conclusion The new indices of abdominal adiposity could help to identify those who were at a high risk of HF, especially in the presence of high BMI or metabolic abnormalities. |
| format | Article |
| id | doaj-art-159d2578bd034b1f9effacde3aa90cfc |
| institution | DOAJ |
| issn | 1475-2891 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
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| series | Nutrition Journal |
| spelling | doaj-art-159d2578bd034b1f9effacde3aa90cfc2025-08-20T02:51:46ZengBMCNutrition Journal1475-28912024-11-0123111110.1186/s12937-024-01048-7Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failureZhijun Wu0Zhe Huang1Liang Sun2Yuang Fu3Shuohua Chen4Shouling Wu5Xiang Gao6Ruijin Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Cardiology, Kailuan General HospitalDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan UniversityDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan UniversityDepartment of Cardiology, Kailuan General HospitalDepartment of Cardiology, Kailuan General HospitalDepartment of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Fudan UniversityAbstract Background The indicators of abdominal obesity have shown to be associated with a high risk of cardiovascular diseases (CVDs), even adjusted for body mass index (BMI). We aimed to investigate the association between neck circumference, waist-to-height ratio (WHtR), Chinese visceral adiposity index (CVAI) and incident heart failure (HF) in Chinese adults. Methods The current study included 86,546 participants from two independent cohorts: the Kailuan I study established in 2006 and the Kailuan study II established in 2008. Participants aged 18–80 years who were free of CVDs or cancer were recruited at baseline. The values of neck circumference, WHtR and CVAI were available in 2014. The trajectory analysis was conducted using repeated measures of WHtR and CVAI in the 2008, 2010, 2012 and 2014 surveys. The incident HF cases were identified via reviewing medical records by cardiologists. Results During a mean follow-up of 5.62 years, 724 incident HF cases were documented. The highest quartiles of neck circumference, WHtR and CVAI respectively, were significantly associated with a high risk of HF compared to the lowest quartiles of adiposity measures (neck circumference: HR:1.30, 95%CI: 1.03–1.65; WHtR: HR:1.49, 95%CI: 1.16–1.92; and CVAI: HR:1.98, 95%CI: 1.48–2.65). The combination of adiposity measures with BMI or metabolic abnormalities jointly predicted incident HF. Presence of hypertension and diabetes appeared to be the major mediators, accounting for ∼ 8.11–24.7% of the associations between three indicators of abdominal obesity and HF risk. Conclusion The new indices of abdominal adiposity could help to identify those who were at a high risk of HF, especially in the presence of high BMI or metabolic abnormalities.https://doi.org/10.1186/s12937-024-01048-7AdiposityNeck circumferenceWaist to height ratioChinese visceral adiposity indexHeart failure |
| spellingShingle | Zhijun Wu Zhe Huang Liang Sun Yuang Fu Shuohua Chen Shouling Wu Xiang Gao Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure Nutrition Journal Adiposity Neck circumference Waist to height ratio Chinese visceral adiposity index Heart failure |
| title | Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure |
| title_full | Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure |
| title_fullStr | Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure |
| title_full_unstemmed | Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure |
| title_short | Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure |
| title_sort | neck circumference waist to height ratio chinese visceral adiposity index and incident heart failure |
| topic | Adiposity Neck circumference Waist to height ratio Chinese visceral adiposity index Heart failure |
| url | https://doi.org/10.1186/s12937-024-01048-7 |
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