Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.

The global priorities in the field of infectious diseases are constantly changing. While emerging viral infections have regularly dominated public health attention, which has only intensified after the COVID-19 pandemic, numerous bacterial diseases have previously caused, and continue to cause, sign...

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Main Authors: Tshokey Tshokey, Ablert I Ko, Bart J Currie, Claudia Munoz-Zanzi, Cyrille Goarant, Daniel H Paris, David A B Dance, Direk Limmathurotsakul, Emma Birnie, Eric Bertherat, Gyanendra Gongal, Jackie Benschop, Jelmer Savelkoel, John Stenos, Kartika Saraswati, Matthew T Robinson, Nicholas P J Day, Stephen R Graves, Steven R Belmain, Stuart D Blacksell, Willem J Wiersinga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012796
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author Tshokey Tshokey
Ablert I Ko
Bart J Currie
Claudia Munoz-Zanzi
Cyrille Goarant
Daniel H Paris
David A B Dance
Direk Limmathurotsakul
Emma Birnie
Eric Bertherat
Gyanendra Gongal
Jackie Benschop
Jelmer Savelkoel
John Stenos
Kartika Saraswati
Matthew T Robinson
Nicholas P J Day
Stephen R Graves
Steven R Belmain
Stuart D Blacksell
Willem J Wiersinga
author_facet Tshokey Tshokey
Ablert I Ko
Bart J Currie
Claudia Munoz-Zanzi
Cyrille Goarant
Daniel H Paris
David A B Dance
Direk Limmathurotsakul
Emma Birnie
Eric Bertherat
Gyanendra Gongal
Jackie Benschop
Jelmer Savelkoel
John Stenos
Kartika Saraswati
Matthew T Robinson
Nicholas P J Day
Stephen R Graves
Steven R Belmain
Stuart D Blacksell
Willem J Wiersinga
author_sort Tshokey Tshokey
collection DOAJ
description The global priorities in the field of infectious diseases are constantly changing. While emerging viral infections have regularly dominated public health attention, which has only intensified after the COVID-19 pandemic, numerous bacterial diseases have previously caused, and continue to cause, significant morbidity and mortality-deserving equal attention. Three potentially life-threatening endemic bacterial diseases (leptospirosis, melioidosis, and rickettsioses) are a huge public health concern especially in low- and middle-income countries. Despite their continued threat, these diseases do not receive proportionate attention from global health organizations and are not even included on the WHO list of neglected tropical diseases (NTDs). This, in turn, has led to a vicious circle of neglect with continued, yet conceivably preventable, hospitalizations and deaths each year especially in the vulnerable population. This is a call from a group of multi-institutional experts on the urgent need to directly address the circle of neglect and raise support in terms of funding, research, surveillance, diagnostics, and therapeutics to alleviate the burden of these 3 diseases.
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institution Kabale University
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1935-2735
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS Neglected Tropical Diseases
spelling doaj-art-159a8d4a872748d39eeb6f638b2e1e542025-02-05T05:33:27ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352025-01-01191e001279610.1371/journal.pntd.0012796Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.Tshokey TshokeyAblert I KoBart J CurrieClaudia Munoz-ZanziCyrille GoarantDaniel H ParisDavid A B DanceDirek LimmathurotsakulEmma BirnieEric BertheratGyanendra GongalJackie BenschopJelmer SavelkoelJohn StenosKartika SaraswatiMatthew T RobinsonNicholas P J DayStephen R GravesSteven R BelmainStuart D BlacksellWillem J WiersingaThe global priorities in the field of infectious diseases are constantly changing. While emerging viral infections have regularly dominated public health attention, which has only intensified after the COVID-19 pandemic, numerous bacterial diseases have previously caused, and continue to cause, significant morbidity and mortality-deserving equal attention. Three potentially life-threatening endemic bacterial diseases (leptospirosis, melioidosis, and rickettsioses) are a huge public health concern especially in low- and middle-income countries. Despite their continued threat, these diseases do not receive proportionate attention from global health organizations and are not even included on the WHO list of neglected tropical diseases (NTDs). This, in turn, has led to a vicious circle of neglect with continued, yet conceivably preventable, hospitalizations and deaths each year especially in the vulnerable population. This is a call from a group of multi-institutional experts on the urgent need to directly address the circle of neglect and raise support in terms of funding, research, surveillance, diagnostics, and therapeutics to alleviate the burden of these 3 diseases.https://doi.org/10.1371/journal.pntd.0012796
spellingShingle Tshokey Tshokey
Ablert I Ko
Bart J Currie
Claudia Munoz-Zanzi
Cyrille Goarant
Daniel H Paris
David A B Dance
Direk Limmathurotsakul
Emma Birnie
Eric Bertherat
Gyanendra Gongal
Jackie Benschop
Jelmer Savelkoel
John Stenos
Kartika Saraswati
Matthew T Robinson
Nicholas P J Day
Stephen R Graves
Steven R Belmain
Stuart D Blacksell
Willem J Wiersinga
Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
PLoS Neglected Tropical Diseases
title Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
title_full Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
title_fullStr Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
title_full_unstemmed Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
title_short Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.
title_sort leptospirosis melioidosis and rickettsioses in the vicious circle of neglect
url https://doi.org/10.1371/journal.pntd.0012796
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