Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopes

Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopes

Abstract Background Coinfection with multiple viruses is a common occurrence in the pig industry. Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) are two significant pathogens, with a notable prevalence of their coinfection observed in clinical settin...

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Bibliographic Details
Main Authors: Jun Ma, Xun Xiao, Yanrong Zhou, Wen Huang, Jie Sun, Xinjian Chang, Shaobo Xiao, Liurong Fang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Porcine reproductive and respiratory syndrome virus
Porcine circovirus type 2
Virus-like particles
Nanoparticle vaccine
Baculovirus expression
Online Access:https://doi.org/10.1186/s12951-025-03514-8
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