The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma
Purpose. To compare long-term effects of trabeculectomy on pseudoexfoliation glaucoma (PXG) and primary open-angle glaucoma (POAG). Methods. This retrospective case-control study included 53 eyes of PXG and 76 eyes of POAG. Intraocular pressure (IOP), number of antiglaucoma medications used, surgica...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/1723691 |
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| author | Fan Li Guangxian Tang Hengli Zhang Xiaowei Yan Lihua Ma Yulei Geng |
| author_facet | Fan Li Guangxian Tang Hengli Zhang Xiaowei Yan Lihua Ma Yulei Geng |
| author_sort | Fan Li |
| collection | DOAJ |
| description | Purpose. To compare long-term effects of trabeculectomy on pseudoexfoliation glaucoma (PXG) and primary open-angle glaucoma (POAG). Methods. This retrospective case-control study included 53 eyes of PXG and 76 eyes of POAG. Intraocular pressure (IOP), number of antiglaucoma medications used, surgical success rate, and occurrence of complications were observed and statistically analyzed in both groups at 3 and 6 months and at 1, 3, and 5 years after trabeculectomy. Surgical success was defined according to the following 3 criteria: (1) IOP ≤ 21 mmHg; (2) IOP ≤ 18 mmHg; (3) IOP ≤ 15 mmHg. Complete success is defined as patients met these criteria without medical treatment, and qualified success is defined as patients met these criteria with medical treatment (≤3 medications). Cumulative probabilities of success were compared using the Kaplan–Meier survival analysis. Results. For the 3 criteria, there were no statistically significant differences in complete and qualified success rates between the two groups at 3 and 6 months after trabeculectomy (P>0.05). For criterion A, complete success rates in PXG at 3 and 5 years after surgery were lower than those in POAG; for criterion B, complete and qualified success rates in PXG at 3 and 5 years after surgery were lower than those in POAG; for criterion C, complete and qualified success rates in PXG at 1, 3, and 5 years after surgery were lower than those in POAG, the differences were statistically significant (P<0.05). Conclusions. The short-term success rates of both types of glaucoma were similar; however, the long-term success rate of PXG was significantly lower, and it was difficult to achieve long-term control of IOP at a low target level. |
| format | Article |
| id | doaj-art-158ba15066d94827b0cf9445343b4078 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-158ba15066d94827b0cf9445343b40782025-02-03T00:58:41ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/17236911723691The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle GlaucomaFan Li0Guangxian Tang1Hengli Zhang2Xiaowei Yan3Lihua Ma4Yulei Geng5Department of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaDepartment of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaDepartment of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaDepartment of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaDepartment of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaDepartment of Ophthalmology, Shijiazhuang No. 1 Hospital, Hebei 050000, ChinaPurpose. To compare long-term effects of trabeculectomy on pseudoexfoliation glaucoma (PXG) and primary open-angle glaucoma (POAG). Methods. This retrospective case-control study included 53 eyes of PXG and 76 eyes of POAG. Intraocular pressure (IOP), number of antiglaucoma medications used, surgical success rate, and occurrence of complications were observed and statistically analyzed in both groups at 3 and 6 months and at 1, 3, and 5 years after trabeculectomy. Surgical success was defined according to the following 3 criteria: (1) IOP ≤ 21 mmHg; (2) IOP ≤ 18 mmHg; (3) IOP ≤ 15 mmHg. Complete success is defined as patients met these criteria without medical treatment, and qualified success is defined as patients met these criteria with medical treatment (≤3 medications). Cumulative probabilities of success were compared using the Kaplan–Meier survival analysis. Results. For the 3 criteria, there were no statistically significant differences in complete and qualified success rates between the two groups at 3 and 6 months after trabeculectomy (P>0.05). For criterion A, complete success rates in PXG at 3 and 5 years after surgery were lower than those in POAG; for criterion B, complete and qualified success rates in PXG at 3 and 5 years after surgery were lower than those in POAG; for criterion C, complete and qualified success rates in PXG at 1, 3, and 5 years after surgery were lower than those in POAG, the differences were statistically significant (P<0.05). Conclusions. The short-term success rates of both types of glaucoma were similar; however, the long-term success rate of PXG was significantly lower, and it was difficult to achieve long-term control of IOP at a low target level.http://dx.doi.org/10.1155/2020/1723691 |
| spellingShingle | Fan Li Guangxian Tang Hengli Zhang Xiaowei Yan Lihua Ma Yulei Geng The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma Journal of Ophthalmology |
| title | The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma |
| title_full | The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma |
| title_fullStr | The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma |
| title_full_unstemmed | The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma |
| title_short | The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma |
| title_sort | effects of trabeculectomy on pseudoexfoliation glaucoma and primary open angle glaucoma |
| url | http://dx.doi.org/10.1155/2020/1723691 |
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