Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method
Allylation of aldehydes was employed in combination with ring-closing metathesis (RCM) and oxidation reactions to achieve the synthesis of cyclic conjugated ketones. The synthetic strategy involved RCM of the mutual homoallylic alcohol intermediate followed by oxidation reaction to afford the six-me...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Results in Chemistry |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624006398 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832583068366405632 |
|---|---|
| author | Jorge Cruz-Huerta Ericka Santacruz Alejandro Castro Jorge García-Dávila Amado Grandes-Blanco |
| author_facet | Jorge Cruz-Huerta Ericka Santacruz Alejandro Castro Jorge García-Dávila Amado Grandes-Blanco |
| author_sort | Jorge Cruz-Huerta |
| collection | DOAJ |
| description | Allylation of aldehydes was employed in combination with ring-closing metathesis (RCM) and oxidation reactions to achieve the synthesis of cyclic conjugated ketones. The synthetic strategy involved RCM of the mutual homoallylic alcohol intermediate followed by oxidation reaction to afford the six-membered cyclic enone. Moreover, when oxidation and RCM were completed successively, the five-membered cyclic enone was obtained. |
| format | Article |
| id | doaj-art-157e16b96e5845638219d2f48155a15f |
| institution | Kabale University |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-157e16b96e5845638219d2f48155a15f2025-01-29T05:00:38ZengElsevierResults in Chemistry2211-71562025-01-0113101943Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation methodJorge Cruz-Huerta0Ericka Santacruz1Alejandro Castro2Jorge García-Dávila3Amado Grandes-Blanco4Universidad Politécnica de Tlaxcala, Av. Universidad Politécnica No. 1, San Pedro Xalcatzinco, 90199 Tepeyanco, Tlax., MéxicoUniversidad Politécnica de Tlaxcala, Av. Universidad Politécnica No. 1, San Pedro Xalcatzinco, 90199 Tepeyanco, Tlax., MéxicoUniversidad Politécnica de Tlaxcala, Av. Universidad Politécnica No. 1, San Pedro Xalcatzinco, 90199 Tepeyanco, Tlax., México; Corresponding author.Universidad Politécnica de Tlaxcala, Av. Universidad Politécnica No. 1, San Pedro Xalcatzinco, 90199 Tepeyanco, Tlax., MéxicoUniversidad Autónoma de Tlaxcala, Ribereña S/N, Centro, 90000 Tlaxcala, Tlax., MéxicoAllylation of aldehydes was employed in combination with ring-closing metathesis (RCM) and oxidation reactions to achieve the synthesis of cyclic conjugated ketones. The synthetic strategy involved RCM of the mutual homoallylic alcohol intermediate followed by oxidation reaction to afford the six-membered cyclic enone. Moreover, when oxidation and RCM were completed successively, the five-membered cyclic enone was obtained.http://www.sciencedirect.com/science/article/pii/S2211715624006398 |
| spellingShingle | Jorge Cruz-Huerta Ericka Santacruz Alejandro Castro Jorge García-Dávila Amado Grandes-Blanco Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method Results in Chemistry |
| title | Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method |
| title_full | Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method |
| title_fullStr | Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method |
| title_full_unstemmed | Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method |
| title_short | Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method |
| title_sort | divergent synthesis of cyclic ketones via a ring closing metathesis and oxidation method |
| url | http://www.sciencedirect.com/science/article/pii/S2211715624006398 |
| work_keys_str_mv | AT jorgecruzhuerta divergentsynthesisofcyclicketonesviaaringclosingmetathesisandoxidationmethod AT erickasantacruz divergentsynthesisofcyclicketonesviaaringclosingmetathesisandoxidationmethod AT alejandrocastro divergentsynthesisofcyclicketonesviaaringclosingmetathesisandoxidationmethod AT jorgegarciadavila divergentsynthesisofcyclicketonesviaaringclosingmetathesisandoxidationmethod AT amadograndesblanco divergentsynthesisofcyclicketonesviaaringclosingmetathesisandoxidationmethod |