Primary Cutaneous Mantle Cell Lymphoma: A Case Report
Primary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/394596 |
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| author | L. D. Mazzuoccolo G. A. Castro Perez I. Sorin A. I. Bravo |
| author_facet | L. D. Mazzuoccolo G. A. Castro Perez I. Sorin A. I. Bravo |
| author_sort | L. D. Mazzuoccolo |
| collection | DOAJ |
| description | Primary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic options. In this case, we describe the clinical, histopathological, immunohistochemical, and molecular characteristics of a new case of primary cutaneous MCL. |
| format | Article |
| id | doaj-art-1561edcd12b640cd873963d0599f1c05 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-1561edcd12b640cd873963d0599f1c052025-02-03T06:08:09ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712013-01-01201310.1155/2013/394596394596Primary Cutaneous Mantle Cell Lymphoma: A Case ReportL. D. Mazzuoccolo0G. A. Castro Perez1I. Sorin2A. I. Bravo3HIGA. Eva Perón, Gral San Martin, Buenos Aires, ArgentinaHIGA. Eva Perón, Gral San Martin, Buenos Aires, ArgentinaDermatology Unit, HIGA. Eva Perón, Gral San Martin, Buenos Aires, ArgentinaDermatology Unit, HIGA. Eva Perón, Gral San Martin, Buenos Aires, ArgentinaPrimary cutaneous mantle cell lymphoma (MCL) is a rare cutaneous proliferation of naive pregerminal CD-5 positive B cells in the skin with no extracutaneous involvement. Overexpression of cyclin D1 is pathognomonic of this condition, and surgery and radiation therapy are the most common therapeutic options. In this case, we describe the clinical, histopathological, immunohistochemical, and molecular characteristics of a new case of primary cutaneous MCL.http://dx.doi.org/10.1155/2013/394596 |
| spellingShingle | L. D. Mazzuoccolo G. A. Castro Perez I. Sorin A. I. Bravo Primary Cutaneous Mantle Cell Lymphoma: A Case Report Case Reports in Dermatological Medicine |
| title | Primary Cutaneous Mantle Cell Lymphoma: A Case Report |
| title_full | Primary Cutaneous Mantle Cell Lymphoma: A Case Report |
| title_fullStr | Primary Cutaneous Mantle Cell Lymphoma: A Case Report |
| title_full_unstemmed | Primary Cutaneous Mantle Cell Lymphoma: A Case Report |
| title_short | Primary Cutaneous Mantle Cell Lymphoma: A Case Report |
| title_sort | primary cutaneous mantle cell lymphoma a case report |
| url | http://dx.doi.org/10.1155/2013/394596 |
| work_keys_str_mv | AT ldmazzuoccolo primarycutaneousmantlecelllymphomaacasereport AT gacastroperez primarycutaneousmantlecelllymphomaacasereport AT isorin primarycutaneousmantlecelllymphomaacasereport AT aibravo primarycutaneousmantlecelllymphomaacasereport |