National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study

Background/Aims: The standard guideline for the management Helicobacter pylori infection in Korean children is not present until now. In present study, we conducted the questionnaire survey to investigate the real situation of H. pylori eradication in children. Materials and Methods: Questionnaire c...

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Main Authors: Jong-Hyuk Youn, Sin Jae Kim, Ji-Hyun Seo, Jae-Young Kim, Hee-Shang Youn, Jae Sung Ko, Kyung Mo Kim, Ju-Young Chung
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2017-12-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.195
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author Jong-Hyuk Youn
Sin Jae Kim
Ji-Hyun Seo
Jae-Young Kim
Hee-Shang Youn
Jae Sung Ko
Kyung Mo Kim
Ju-Young Chung
author_facet Jong-Hyuk Youn
Sin Jae Kim
Ji-Hyun Seo
Jae-Young Kim
Hee-Shang Youn
Jae Sung Ko
Kyung Mo Kim
Ju-Young Chung
author_sort Jong-Hyuk Youn
collection DOAJ
description Background/Aims: The standard guideline for the management Helicobacter pylori infection in Korean children is not present until now. In present study, we conducted the questionnaire survey to investigate the real situation of H. pylori eradication in children. Materials and Methods: Questionnaire concerning the indications of H. pylori eradication, the first choice of treatment modality, the decision method of eradication result, experience of eradication failure, the second choice of treatment modality was sent to doctors who are members of the Korean Society for Pediatric Gastorenterology, Hepatology, and Nutrition. Results: A total of 28 doctors (90.3%) answered the questionnaires among 31 doctors. The most common indication for eradication of H. pylori was peptic ulcer (n=24) followed by chronic abdominal pain (n=17) and positive family history of gastric cancer (n=12). The most common choice of first-line eradication therapy was omeprazole, amoxicillin, clarithromycin triple therapy (n=21) and followed by bismuth subsalicylate, amoxicillin, metronidazole, clarithromycin quadruple therapy (n=7). The results of treatment were judged by C¹³-urea breath test after 2 months later in 19 doctors (67.8%). Twenty four (85.7%) out of 28 doctors had experienced treatment failure. The most common second-line therapy was the sequential therapy (58.3%, 14 doctors among 24). Conclusions: This was the first study for the survey of the treatment of H. pylori infection to Korean pediatricians. The results of this study showed that most pediatric gastroenterologists used to treat H. pylori infection according to the textbook and the common use of bismuth-based quadruple therapy for the first-line treatment was notable.
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issn 1738-3331
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publishDate 2017-12-01
publisher Korean College of Helicobacter and Upper Gastrointestinal Research
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spelling doaj-art-1551952929e74dfeb30db5ebe8d6569d2025-08-20T02:41:55ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-12-0117419519910.7704/kjhugr.2017.17.4.195kjhugr.2017.17.4.195National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot StudyJong-Hyuk Youn0Sin Jae Kim1Ji-Hyun Seo2Jae-Young Kim3Hee-Shang Youn4Jae Sung Ko5Kyung Mo Kim6Ju-Young Chung7Department of Pediatrics and Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics and Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics and Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics, Gyeongsang National University Hospital, Changwon, KoreaDepartment of Pediatrics and Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Ulsan, KoreaDepartment of Pediatrics, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, KoreaBackground/Aims: The standard guideline for the management Helicobacter pylori infection in Korean children is not present until now. In present study, we conducted the questionnaire survey to investigate the real situation of H. pylori eradication in children. Materials and Methods: Questionnaire concerning the indications of H. pylori eradication, the first choice of treatment modality, the decision method of eradication result, experience of eradication failure, the second choice of treatment modality was sent to doctors who are members of the Korean Society for Pediatric Gastorenterology, Hepatology, and Nutrition. Results: A total of 28 doctors (90.3%) answered the questionnaires among 31 doctors. The most common indication for eradication of H. pylori was peptic ulcer (n=24) followed by chronic abdominal pain (n=17) and positive family history of gastric cancer (n=12). The most common choice of first-line eradication therapy was omeprazole, amoxicillin, clarithromycin triple therapy (n=21) and followed by bismuth subsalicylate, amoxicillin, metronidazole, clarithromycin quadruple therapy (n=7). The results of treatment were judged by C¹³-urea breath test after 2 months later in 19 doctors (67.8%). Twenty four (85.7%) out of 28 doctors had experienced treatment failure. The most common second-line therapy was the sequential therapy (58.3%, 14 doctors among 24). Conclusions: This was the first study for the survey of the treatment of H. pylori infection to Korean pediatricians. The results of this study showed that most pediatric gastroenterologists used to treat H. pylori infection according to the textbook and the common use of bismuth-based quadruple therapy for the first-line treatment was notable.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.195ChildHelicobacter pyloriTherapeutics
spellingShingle Jong-Hyuk Youn
Sin Jae Kim
Ji-Hyun Seo
Jae-Young Kim
Hee-Shang Youn
Jae Sung Ko
Kyung Mo Kim
Ju-Young Chung
National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Child
Helicobacter pylori
Therapeutics
title National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
title_full National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
title_fullStr National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
title_full_unstemmed National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
title_short National Survey Assessing Treatment of Helicobacter pylori Infection in Korean Children: A Pilot Study
title_sort national survey assessing treatment of helicobacter pylori infection in korean children a pilot study
topic Child
Helicobacter pylori
Therapeutics
url http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.195
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