Dynamics of oxylipin biosynthesis in systemic inflammation: insights from a large animal model of endotoxemia
IntroductionEndotoxemia, marked by the presence of bacterial lipopolysaccharide (LPS) in the bloodstream, induces acute inflammation and is implicated in both mortality and chronic disease across species. LPS stimulates lipolysis and activates cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595888/full |
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