Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology

Adenoid cystic carcinoma is a tumor that mainly arises from salivary glands and is present rarely in airways with nonspecific symptoms. Diagnosis based on bronchial washing cytology is rarely reported because this tumor is usually lined by normal mucosa. A 35-year-old woman was referred to our cente...

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Main Authors: Maryam Mohammadnia, Massood Hosseinzadeh, Perikala Vijayananda Kumar, Sahand Mohammadzadeh
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/6543097
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author Maryam Mohammadnia
Massood Hosseinzadeh
Perikala Vijayananda Kumar
Sahand Mohammadzadeh
author_facet Maryam Mohammadnia
Massood Hosseinzadeh
Perikala Vijayananda Kumar
Sahand Mohammadzadeh
author_sort Maryam Mohammadnia
collection DOAJ
description Adenoid cystic carcinoma is a tumor that mainly arises from salivary glands and is present rarely in airways with nonspecific symptoms. Diagnosis based on bronchial washing cytology is rarely reported because this tumor is usually lined by normal mucosa. A 35-year-old woman was referred to our center as a case of unresponsive asthma and hemoptysis for the past year. CT scan showed tracheal mass. Bronchoscopy was done followed by bronchial washing cytology and biopsy. Cytology smears revealed sheets and three-dimensional clusters of small cells, and some of them arranged around hyaline mucoid globules. Cell block and biopsy showed classic pathological findings of adenoid cystic carcinoma. Adenoid cystic carcinoma of the airways can be manifested with nonspecific symptoms and should be considered in the differential diagnosis of airway diseases and asthma. This tumor is rarely seen in the bronchial washing specimen. Characteristic cytological findings and using cell block preparation differentiate adenoid cystic carcinoma from other tumors.
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institution Kabale University
issn 1687-9627
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language English
publishDate 2020-01-01
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series Case Reports in Medicine
spelling doaj-art-15361d8a22ac451b8dbacc47d032b4c32025-02-03T06:43:39ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/65430976543097Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing CytologyMaryam Mohammadnia0Massood Hosseinzadeh1Perikala Vijayananda Kumar2Sahand Mohammadzadeh3Department of Pathology, Shiraz University of Medical Science, Shiraz, IranDepartment of Pathology, Shiraz University of Medical Science, Shiraz, IranDepartment of Pathology, Shiraz University of Medical Science, Shiraz, IranDepartment of Pathology, Shiraz University of Medical Science, Shiraz, IranAdenoid cystic carcinoma is a tumor that mainly arises from salivary glands and is present rarely in airways with nonspecific symptoms. Diagnosis based on bronchial washing cytology is rarely reported because this tumor is usually lined by normal mucosa. A 35-year-old woman was referred to our center as a case of unresponsive asthma and hemoptysis for the past year. CT scan showed tracheal mass. Bronchoscopy was done followed by bronchial washing cytology and biopsy. Cytology smears revealed sheets and three-dimensional clusters of small cells, and some of them arranged around hyaline mucoid globules. Cell block and biopsy showed classic pathological findings of adenoid cystic carcinoma. Adenoid cystic carcinoma of the airways can be manifested with nonspecific symptoms and should be considered in the differential diagnosis of airway diseases and asthma. This tumor is rarely seen in the bronchial washing specimen. Characteristic cytological findings and using cell block preparation differentiate adenoid cystic carcinoma from other tumors.http://dx.doi.org/10.1155/2020/6543097
spellingShingle Maryam Mohammadnia
Massood Hosseinzadeh
Perikala Vijayananda Kumar
Sahand Mohammadzadeh
Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
Case Reports in Medicine
title Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
title_full Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
title_fullStr Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
title_full_unstemmed Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
title_short Tracheal Adenoid Cystic Carcinoma Presented with Chronic Asthma Diagnosed by Bronchial Washing Cytology
title_sort tracheal adenoid cystic carcinoma presented with chronic asthma diagnosed by bronchial washing cytology
url http://dx.doi.org/10.1155/2020/6543097
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AT massoodhosseinzadeh trachealadenoidcysticcarcinomapresentedwithchronicasthmadiagnosedbybronchialwashingcytology
AT perikalavijayanandakumar trachealadenoidcysticcarcinomapresentedwithchronicasthmadiagnosedbybronchialwashingcytology
AT sahandmohammadzadeh trachealadenoidcysticcarcinomapresentedwithchronicasthmadiagnosedbybronchialwashingcytology