Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations
Purpose. Motor freezing, the inability to produce effective movement, is associated with decreasing amplitude, hastening of movement, and poor coordination. We investigated how manipulations of movement amplitude and cadence affect upper extremity (UE) coordination as measured by the phase coordinat...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2013/595378 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561892823924736 |
|---|---|
| author | April J. Williams Daniel S. Peterson Michele Ionno Kristen A. Pickett Gammon M. Earhart |
| author_facet | April J. Williams Daniel S. Peterson Michele Ionno Kristen A. Pickett Gammon M. Earhart |
| author_sort | April J. Williams |
| collection | DOAJ |
| description | Purpose. Motor freezing, the inability to produce effective movement, is associated with decreasing amplitude, hastening of movement, and poor coordination. We investigated how manipulations of movement amplitude and cadence affect upper extremity (UE) coordination as measured by the phase coordination index (PCI)—only previously measured in gait—and freezing of the upper extremity (FO-UE) in people with Parkinson's disease (PD) who experience freezing of gait (PD + FOG), do not experience FOG (PD-FOG), and healthy controls. Methods. Twenty-seven participants with PD and 18 healthy older adults made alternating bimanual movements between targets under four conditions: Baseline; Fast; Small; SmallFast. Kinematic data were recorded and analyzed for PCI and FO-UE events. PCI and FO-UE were compared across groups and conditions. Correlations between UE PCI, gait PCI, FO-UE, and Freezing of Gait Questionnaire (FOG-Q) were determined. Results. PD + FOG had poorer coordination than healthy old during SmallFast. UE coordination correlated with number of FO-UE episodes in two conditions and FOG-Q score in one. No differences existed between PD−/+FOG in coordination or number of FO-UE episodes. Conclusions. Dyscoordination and FO-UE can be elicited by manipulating cadence and amplitude of an alternating bimanual task. It remains unclear whether FO-UE and FOG share common mechanisms. |
| format | Article |
| id | doaj-art-14d1565095d14e5eb5309977dfea5b59 |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-14d1565095d14e5eb5309977dfea5b592025-02-03T01:23:54ZengWileyParkinson's Disease2090-80832042-00802013-01-01201310.1155/2013/595378595378Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence ManipulationsApril J. Williams0Daniel S. Peterson1Michele Ionno2Kristen A. Pickett3Gammon M. Earhart4Program in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USAProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USAProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USAProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USAProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USAPurpose. Motor freezing, the inability to produce effective movement, is associated with decreasing amplitude, hastening of movement, and poor coordination. We investigated how manipulations of movement amplitude and cadence affect upper extremity (UE) coordination as measured by the phase coordination index (PCI)—only previously measured in gait—and freezing of the upper extremity (FO-UE) in people with Parkinson's disease (PD) who experience freezing of gait (PD + FOG), do not experience FOG (PD-FOG), and healthy controls. Methods. Twenty-seven participants with PD and 18 healthy older adults made alternating bimanual movements between targets under four conditions: Baseline; Fast; Small; SmallFast. Kinematic data were recorded and analyzed for PCI and FO-UE events. PCI and FO-UE were compared across groups and conditions. Correlations between UE PCI, gait PCI, FO-UE, and Freezing of Gait Questionnaire (FOG-Q) were determined. Results. PD + FOG had poorer coordination than healthy old during SmallFast. UE coordination correlated with number of FO-UE episodes in two conditions and FOG-Q score in one. No differences existed between PD−/+FOG in coordination or number of FO-UE episodes. Conclusions. Dyscoordination and FO-UE can be elicited by manipulating cadence and amplitude of an alternating bimanual task. It remains unclear whether FO-UE and FOG share common mechanisms.http://dx.doi.org/10.1155/2013/595378 |
| spellingShingle | April J. Williams Daniel S. Peterson Michele Ionno Kristen A. Pickett Gammon M. Earhart Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations Parkinson's Disease |
| title | Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations |
| title_full | Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations |
| title_fullStr | Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations |
| title_full_unstemmed | Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations |
| title_short | Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations |
| title_sort | upper extremity freezing and dyscoordination in parkinson s disease effects of amplitude and cadence manipulations |
| url | http://dx.doi.org/10.1155/2013/595378 |
| work_keys_str_mv | AT apriljwilliams upperextremityfreezinganddyscoordinationinparkinsonsdiseaseeffectsofamplitudeandcadencemanipulations AT danielspeterson upperextremityfreezinganddyscoordinationinparkinsonsdiseaseeffectsofamplitudeandcadencemanipulations AT micheleionno upperextremityfreezinganddyscoordinationinparkinsonsdiseaseeffectsofamplitudeandcadencemanipulations AT kristenapickett upperextremityfreezinganddyscoordinationinparkinsonsdiseaseeffectsofamplitudeandcadencemanipulations AT gammonmearhart upperextremityfreezinganddyscoordinationinparkinsonsdiseaseeffectsofamplitudeandcadencemanipulations |