Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study
Background. To reduce the incidence of microbial colonization of suture material, Triclosan- (TC-)coated suture materials have been developed. The aim of this study was to assess the incidence of suture-related complications (SRC) in breast surgery with and without the use of TC-coated sutures. Meth...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.1155/2012/819578 |
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| author | Enora Laas Cécile Poilroux Corinne Bézu Charles Coutant Serge Uzan Roman Rouzier Elisabeth Chéreau |
| author_facet | Enora Laas Cécile Poilroux Corinne Bézu Charles Coutant Serge Uzan Roman Rouzier Elisabeth Chéreau |
| author_sort | Enora Laas |
| collection | DOAJ |
| description | Background. To reduce the incidence of microbial colonization of suture material, Triclosan- (TC-)coated suture materials have been developed. The aim of this study was to assess the incidence of suture-related complications (SRC) in breast surgery with and without the use of TC-coated sutures. Methods. We performed a study on two consecutive periods: 92 patients underwent breast surgery with conventional sutures (Group 1) and 98 with TC-coated sutures (Group 2). We performed subgroups analyses and developed a model to predict SRC in Group 1 and tested its clinical efficacy in Group 2 using a nomogram-based approach. Results. The SRC rates were 13% in Group 1 and 8% in Group 2. We found that some subgroups may benefit from TC-coated sutures. The discrimination obtained from a logistic regression model developed in Group 1 and based on multifocality, age and axillary lymphadenectomy was 0.88 (95% CI 0.77–0.95) (). There was a significant difference in Group 2 between predicted probabilities and observed percentages (). The predicted and observed proportions of complications in the high-risk group were 38% and 13%, respectively. Conclusion. This study used individual predictions of SRC and showed that using TC-coated suture may prevent SRC. This was particularly significant in high-risk patients. |
| format | Article |
| id | doaj-art-14a7616263ff4c2ca2c2889f1dc5cf3c |
| institution | Kabale University |
| issn | 2090-3170 2090-3189 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-14a7616263ff4c2ca2c2889f1dc5cf3c2025-02-03T06:11:42ZengWileyInternational Journal of Breast Cancer2090-31702090-31892012-01-01201210.1155/2012/819578819578Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective StudyEnora Laas0Cécile Poilroux1Corinne Bézu2Charles Coutant3Serge Uzan4Roman Rouzier5Elisabeth Chéreau6 Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, France Service de Gynécologie-Obtétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie-Paris 6 75020 Paris, FranceBackground. To reduce the incidence of microbial colonization of suture material, Triclosan- (TC-)coated suture materials have been developed. The aim of this study was to assess the incidence of suture-related complications (SRC) in breast surgery with and without the use of TC-coated sutures. Methods. We performed a study on two consecutive periods: 92 patients underwent breast surgery with conventional sutures (Group 1) and 98 with TC-coated sutures (Group 2). We performed subgroups analyses and developed a model to predict SRC in Group 1 and tested its clinical efficacy in Group 2 using a nomogram-based approach. Results. The SRC rates were 13% in Group 1 and 8% in Group 2. We found that some subgroups may benefit from TC-coated sutures. The discrimination obtained from a logistic regression model developed in Group 1 and based on multifocality, age and axillary lymphadenectomy was 0.88 (95% CI 0.77–0.95) (). There was a significant difference in Group 2 between predicted probabilities and observed percentages (). The predicted and observed proportions of complications in the high-risk group were 38% and 13%, respectively. Conclusion. This study used individual predictions of SRC and showed that using TC-coated suture may prevent SRC. This was particularly significant in high-risk patients.http://dx.doi.org/10.1155/2012/819578 |
| spellingShingle | Enora Laas Cécile Poilroux Corinne Bézu Charles Coutant Serge Uzan Roman Rouzier Elisabeth Chéreau Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study International Journal of Breast Cancer |
| title | Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study |
| title_full | Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study |
| title_fullStr | Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study |
| title_full_unstemmed | Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study |
| title_short | Antibacterial-Coated Suture in Reducing Surgical Site Infection in Breast Surgery: A Prospective Study |
| title_sort | antibacterial coated suture in reducing surgical site infection in breast surgery a prospective study |
| url | http://dx.doi.org/10.1155/2012/819578 |
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