Coagulability in Obstructive Sleep Apnea
BACKGROUND: Obstructive sleep apnea (OSA) is a common disorder that affects both quality of life and cardiovascular health. The causal link between OSA and cardiovascular morbidity/mortality remains elusive. One possible explanation is that repeated episodes of nocturnal hypoxia lead to a hypercoagu...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2011/924629 |
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| _version_ | 1832553925494964224 |
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| author | Christina Liak Michael Fitzpatrick |
| author_facet | Christina Liak Michael Fitzpatrick |
| author_sort | Christina Liak |
| collection | DOAJ |
| description | BACKGROUND: Obstructive sleep apnea (OSA) is a common disorder that affects both quality of life and cardiovascular health. The causal link between OSA and cardiovascular morbidity/mortality remains elusive. One possible explanation is that repeated episodes of nocturnal hypoxia lead to a hypercoagulable state that predisposes patients to thrombotic events. There is evidence supporting a wide array of hematological changes that affect hemostasis (eg, increased hematocrit, blood viscosity, platelet activation, clotting factors and decreased fibrinolytic activity). |
| format | Article |
| id | doaj-art-1499b9d8b6954729bdbafbce14c143a4 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-1499b9d8b6954729bdbafbce14c143a42025-02-03T05:52:45ZengWileyCanadian Respiratory Journal1198-22412011-01-0118633834810.1155/2011/924629Coagulability in Obstructive Sleep ApneaChristina Liak0Michael Fitzpatrick1Division of Respirology & Critical Care Medicine, Department of Medicine, Queen’s University, Kingston, Ontario, CanadaDivision of Respirology & Critical Care Medicine, Department of Medicine, Queen’s University, Kingston, Ontario, CanadaBACKGROUND: Obstructive sleep apnea (OSA) is a common disorder that affects both quality of life and cardiovascular health. The causal link between OSA and cardiovascular morbidity/mortality remains elusive. One possible explanation is that repeated episodes of nocturnal hypoxia lead to a hypercoagulable state that predisposes patients to thrombotic events. There is evidence supporting a wide array of hematological changes that affect hemostasis (eg, increased hematocrit, blood viscosity, platelet activation, clotting factors and decreased fibrinolytic activity).http://dx.doi.org/10.1155/2011/924629 |
| spellingShingle | Christina Liak Michael Fitzpatrick Coagulability in Obstructive Sleep Apnea Canadian Respiratory Journal |
| title | Coagulability in Obstructive Sleep Apnea |
| title_full | Coagulability in Obstructive Sleep Apnea |
| title_fullStr | Coagulability in Obstructive Sleep Apnea |
| title_full_unstemmed | Coagulability in Obstructive Sleep Apnea |
| title_short | Coagulability in Obstructive Sleep Apnea |
| title_sort | coagulability in obstructive sleep apnea |
| url | http://dx.doi.org/10.1155/2011/924629 |
| work_keys_str_mv | AT christinaliak coagulabilityinobstructivesleepapnea AT michaelfitzpatrick coagulabilityinobstructivesleepapnea |