Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman
Primary pleural angiosarcomas are extremely rare. As of 2010, only around 50 case reports have been documented in the literature. Herein, we report the case of a 63-year-old gentleman who presented with a 3-month history of right-sided chest pain, dyspnea, and hemoptysis. Chest X-ray showed bilatera...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2013/974567 |
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| author | Ahmed Abu-Zaid Shamayel Mohammed |
| author_facet | Ahmed Abu-Zaid Shamayel Mohammed |
| author_sort | Ahmed Abu-Zaid |
| collection | DOAJ |
| description | Primary pleural angiosarcomas are extremely rare. As of 2010, only around 50 case reports have been documented in the literature. Herein, we report the case of a 63-year-old gentleman who presented with a 3-month history of right-sided chest pain, dyspnea, and hemoptysis. Chest X-ray showed bilateral pleural effusion with partial bibasilar atelectasis. Ultrasound-guided thoracocentesis showed bloody and exudative pleural fluid. Cytologic examination was negative for malignant cells. An abdominal contrast-enhanced computed tomography (CT) scan showed two right diaphragmatic pleural masses. Whole-body positron emission tomography/computed tomography (PET/CT) scan showed two hypermetabolic fluorodeoxyglucose- (FDG-) avid lesions involving the right diaphragmatic pleura. CT-guided needle-core biopsy was performed and histopathological examination showed neoplastic cells growing mainly in sheets with focal areas suggestive of vascular spaces lined by cytologically malignant epithelioid cells. Immunohistochemical analysis showed strong positivity for vimentin, CD31, CD68, and Fli-1 markers. The overall pathological and immunohistochemical features supported the diagnosis of epithelioid angiosarcoma. The patient was scheduled for surgery in three weeks. Unfortunately, the patient died after one week after discharge secondary to pulseless ventricular tachycardia arrest followed by asystole. Moreover, we also present a brief literature review on pleural angiosarcoma. |
| format | Article |
| id | doaj-art-14813b02ecb74bde930c4c56f151625b |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-14813b02ecb74bde930c4c56f151625b2025-02-03T06:12:10ZengWileyCase Reports in Pulmonology2090-68462090-68542013-01-01201310.1155/2013/974567974567Primary Pleural Angiosarcoma in a 63-Year-Old GentlemanAhmed Abu-Zaid0Shamayel Mohammed1College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi ArabiaDepartment of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center (KFSH&RC), P.O. Box 3354, Riyadh 11211, Saudi ArabiaPrimary pleural angiosarcomas are extremely rare. As of 2010, only around 50 case reports have been documented in the literature. Herein, we report the case of a 63-year-old gentleman who presented with a 3-month history of right-sided chest pain, dyspnea, and hemoptysis. Chest X-ray showed bilateral pleural effusion with partial bibasilar atelectasis. Ultrasound-guided thoracocentesis showed bloody and exudative pleural fluid. Cytologic examination was negative for malignant cells. An abdominal contrast-enhanced computed tomography (CT) scan showed two right diaphragmatic pleural masses. Whole-body positron emission tomography/computed tomography (PET/CT) scan showed two hypermetabolic fluorodeoxyglucose- (FDG-) avid lesions involving the right diaphragmatic pleura. CT-guided needle-core biopsy was performed and histopathological examination showed neoplastic cells growing mainly in sheets with focal areas suggestive of vascular spaces lined by cytologically malignant epithelioid cells. Immunohistochemical analysis showed strong positivity for vimentin, CD31, CD68, and Fli-1 markers. The overall pathological and immunohistochemical features supported the diagnosis of epithelioid angiosarcoma. The patient was scheduled for surgery in three weeks. Unfortunately, the patient died after one week after discharge secondary to pulseless ventricular tachycardia arrest followed by asystole. Moreover, we also present a brief literature review on pleural angiosarcoma.http://dx.doi.org/10.1155/2013/974567 |
| spellingShingle | Ahmed Abu-Zaid Shamayel Mohammed Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman Case Reports in Pulmonology |
| title | Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman |
| title_full | Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman |
| title_fullStr | Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman |
| title_full_unstemmed | Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman |
| title_short | Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman |
| title_sort | primary pleural angiosarcoma in a 63 year old gentleman |
| url | http://dx.doi.org/10.1155/2013/974567 |
| work_keys_str_mv | AT ahmedabuzaid primarypleuralangiosarcomaina63yearoldgentleman AT shamayelmohammed primarypleuralangiosarcomaina63yearoldgentleman |