Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2019/1690153 |
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| author | Suranga M. Rajapaksha Katherine Gerken Todd Archer Patty Lathan Achala S. Liyanage Deb Mlsna Todd E. Mlsna |
| author_facet | Suranga M. Rajapaksha Katherine Gerken Todd Archer Patty Lathan Achala S. Liyanage Deb Mlsna Todd E. Mlsna |
| author_sort | Suranga M. Rajapaksha |
| collection | DOAJ |
| description | Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty if these chewing gums are still dangerous to dogs after they have been partially consumed. In this work, a reliable low-cost analytical method has been developed to quantify the xylitol in sugar-free gum samples. Xylitol was extracted from gum samples using water as a solvent. Extractions were analyzed by GC-MS with direct aqueous injection (DAI). This method was successfully applied to over 120 samples including fresh gum and 5 min, 15 min, and 30 min chewed gum samples. |
| format | Article |
| id | doaj-art-147efedcd4ab485fb3f89562dc68ed43 |
| institution | Kabale University |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-147efedcd4ab485fb3f89562dc68ed432025-02-03T01:02:01ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732019-01-01201910.1155/2019/16901531690153Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous InjectionSuranga M. Rajapaksha0Katherine Gerken1Todd Archer2Patty Lathan3Achala S. Liyanage4Deb Mlsna5Todd E. Mlsna6Department of Chemistry, Mississippi State University, Starkville, MS 39762, USASmall Animal Emergency and Critical Care, The Ohio State University, Veterinary Medical Center, Columbus, OH 43210, USACollege of Veterinary Medicine, Mississippi State, Jackson, MS 39762, USACollege of Veterinary Medicine, Mississippi State, Jackson, MS 39762, USADepartment of Chemistry, Mississippi State University, Starkville, MS 39762, USADepartment of Chemistry, Mississippi State University, Starkville, MS 39762, USADepartment of Chemistry, Mississippi State University, Starkville, MS 39762, USAXylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty if these chewing gums are still dangerous to dogs after they have been partially consumed. In this work, a reliable low-cost analytical method has been developed to quantify the xylitol in sugar-free gum samples. Xylitol was extracted from gum samples using water as a solvent. Extractions were analyzed by GC-MS with direct aqueous injection (DAI). This method was successfully applied to over 120 samples including fresh gum and 5 min, 15 min, and 30 min chewed gum samples.http://dx.doi.org/10.1155/2019/1690153 |
| spellingShingle | Suranga M. Rajapaksha Katherine Gerken Todd Archer Patty Lathan Achala S. Liyanage Deb Mlsna Todd E. Mlsna Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection Journal of Analytical Methods in Chemistry |
| title | Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection |
| title_full | Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection |
| title_fullStr | Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection |
| title_full_unstemmed | Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection |
| title_short | Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection |
| title_sort | extraction and analysis of xylitol in sugar free gum samples by gc ms with direct aqueous injection |
| url | http://dx.doi.org/10.1155/2019/1690153 |
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