Intracellular Targeting of CEA Results in Th1-Type Antibody Responses Following Intradermal Genetic Vaccination by a Needle-Free Jet Injection Device

The route and method of immunization, as well as the cellular localization of the antigen, can influence the generation of an immune response. In general, intramuscular immunization results in Th1 responses, whereas intradermal delivery of DNA by gene gun immunization often results in more Th2 respo...

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Bibliographic Details
Main Authors: Susanne Johansson, Monica Ek, Britta Wahren, Richard Stout, Margaret A. Liu, Kristian Hallermalm
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2007.138
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