Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls
Purpose. Ultrasonography (US) has been demonstrated to be an important tool in the diagnosis of calcium pyrophosphate (CPP) crystal deposition disease. The aim of our study was to individuate and describe possible pitfalls in US detection of such deposits in menisci. Patients and Methods. We enroll...
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| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/181826 |
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| author | Georgios Filippou Antonella Adinolfi Panagiotis Bozios Sauro Lorenzini Valentina Picerno Valentina Di Sabatino Ilaria Bertoldi Dario Gambera Mauro Galeazzi Bruno Frediani |
| author_facet | Georgios Filippou Antonella Adinolfi Panagiotis Bozios Sauro Lorenzini Valentina Picerno Valentina Di Sabatino Ilaria Bertoldi Dario Gambera Mauro Galeazzi Bruno Frediani |
| author_sort | Georgios Filippou |
| collection | DOAJ |
| description | Purpose. Ultrasonography (US) has been demonstrated to be an important tool in the diagnosis of calcium pyrophosphate (CPP) crystal deposition disease. The aim of our study was to individuate and describe possible pitfalls in US detection of such deposits in menisci.
Patients and Methods. We enrolled all patients waiting to undergo knee replacement surgery due to osteoarthritis, for one-month period. Each patient underwent US examination of the knee, focusing on the menisci. After surgery, the menisci were examined by US, macroscopically and microscopically, using the microscopic analysis as the gold standard for CPP deposition.
Results. 11 menisci of 6 patients have been studied. Ex vivo examination of menisci performed better in CPP identification than in vivo examination. The possible reasons of misinterpretation or misdiagnosis of the in vivo exam were identified and are extensively described in the paper. Also a new sign of CPP crystal deposits was found.
Conclusions. This study permitted to highlight some difficulties in CPP crystal detection by US in menisci. Further studies are needed to define completely US CPP crystal aspect and to improve the sensibility and specificity of US in CPP deposition diagnosis. |
| format | Article |
| id | doaj-art-145a0be28f9445c39ec677948830d571 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-145a0be28f9445c39ec677948830d5712025-02-03T01:07:13ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/181826181826Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and PitfallsGeorgios Filippou0Antonella Adinolfi1Panagiotis Bozios2Sauro Lorenzini3Valentina Picerno4Valentina Di Sabatino5Ilaria Bertoldi6Dario Gambera7Mauro Galeazzi8Bruno Frediani9Department of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyOrthopedic Unit, Casa di Cura Rugani, SS 222 Chiantigiana, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neurosciences, Rheumatology Section, University of Siena, Policlinico le Scotte, Viale Bracci, 53100 Siena, ItalyPurpose. Ultrasonography (US) has been demonstrated to be an important tool in the diagnosis of calcium pyrophosphate (CPP) crystal deposition disease. The aim of our study was to individuate and describe possible pitfalls in US detection of such deposits in menisci. Patients and Methods. We enrolled all patients waiting to undergo knee replacement surgery due to osteoarthritis, for one-month period. Each patient underwent US examination of the knee, focusing on the menisci. After surgery, the menisci were examined by US, macroscopically and microscopically, using the microscopic analysis as the gold standard for CPP deposition. Results. 11 menisci of 6 patients have been studied. Ex vivo examination of menisci performed better in CPP identification than in vivo examination. The possible reasons of misinterpretation or misdiagnosis of the in vivo exam were identified and are extensively described in the paper. Also a new sign of CPP crystal deposits was found. Conclusions. This study permitted to highlight some difficulties in CPP crystal detection by US in menisci. Further studies are needed to define completely US CPP crystal aspect and to improve the sensibility and specificity of US in CPP deposition diagnosis.http://dx.doi.org/10.1155/2013/181826 |
| spellingShingle | Georgios Filippou Antonella Adinolfi Panagiotis Bozios Sauro Lorenzini Valentina Picerno Valentina Di Sabatino Ilaria Bertoldi Dario Gambera Mauro Galeazzi Bruno Frediani Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls The Scientific World Journal |
| title | Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls |
| title_full | Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls |
| title_fullStr | Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls |
| title_full_unstemmed | Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls |
| title_short | Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls |
| title_sort | do not hallow until you are out of the wood ultrasonographic detection of cpp crystal deposits in menisci facts and pitfalls |
| url | http://dx.doi.org/10.1155/2013/181826 |
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