Oxi-Inflamm-Aging: a New Theory with Practical Implications
Oxidative stress causes an impairment of the physiological systems essential for maintaining homeostasis, including the immune system. Immune <em>dysregulation</em> leads to a <em>chronic low-grade inflammatory state</em> in aging. This is the basis of the new integrative the...
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| Format: | Article |
| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2016-10-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/3280 |
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| author | Ángel Julio Romero Cabrera Leocadia Amores Hernández |
| author_facet | Ángel Julio Romero Cabrera Leocadia Amores Hernández |
| author_sort | Ángel Julio Romero Cabrera |
| collection | DOAJ |
| description | Oxidative stress causes an impairment of the physiological systems essential for maintaining homeostasis, including the immune system. Immune <em>dysregulation</em> leads to a <em>chronic low-grade inflammatory state</em> in aging. This is the basis of the new integrative theory called oxy-inflamm-aging. The present article describes the foundations of this theory, the current research studies that support it, and its link with the pathogenesis of some age-related diseases. It is concluded that the adoption of a healthy lifestyle from an early age can contribute to a successful aging. The benefits of caloric restriction and antioxidant supplements are still under study in order to prevent <em>oxidative stress </em>and <em>inflammation</em>, and consequently achieve greater longevity and reduce the burden of age-associated diseases. |
| format | Article |
| id | doaj-art-14511dd6bcfc4426ae983d92387eba23 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2016-10-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-14511dd6bcfc4426ae983d92387eba232025-01-30T21:28:50ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2016-10-011455915991349Oxi-Inflamm-Aging: a New Theory with Practical ImplicationsÁngel Julio Romero Cabrera0Leocadia Amores Hernández1Hospital General Universitario Dr. Gustavo Aldereguía Lima. CienfuegosHospital General Universitario Dr. Gustavo Aldereguía Lima. CienfuegosOxidative stress causes an impairment of the physiological systems essential for maintaining homeostasis, including the immune system. Immune <em>dysregulation</em> leads to a <em>chronic low-grade inflammatory state</em> in aging. This is the basis of the new integrative theory called oxy-inflamm-aging. The present article describes the foundations of this theory, the current research studies that support it, and its link with the pathogenesis of some age-related diseases. It is concluded that the adoption of a healthy lifestyle from an early age can contribute to a successful aging. The benefits of caloric restriction and antioxidant supplements are still under study in order to prevent <em>oxidative stress </em>and <em>inflammation</em>, and consequently achieve greater longevity and reduce the burden of age-associated diseases.http://medisur.sld.cu/index.php/medisur/article/view/3280envejecimientoestrés oxidativoinflamaciónenfermedades crónicaslongevidad |
| spellingShingle | Ángel Julio Romero Cabrera Leocadia Amores Hernández Oxi-Inflamm-Aging: a New Theory with Practical Implications Medisur envejecimiento estrés oxidativo inflamación enfermedades crónicas longevidad |
| title | Oxi-Inflamm-Aging: a New Theory with Practical Implications |
| title_full | Oxi-Inflamm-Aging: a New Theory with Practical Implications |
| title_fullStr | Oxi-Inflamm-Aging: a New Theory with Practical Implications |
| title_full_unstemmed | Oxi-Inflamm-Aging: a New Theory with Practical Implications |
| title_short | Oxi-Inflamm-Aging: a New Theory with Practical Implications |
| title_sort | oxi inflamm aging a new theory with practical implications |
| topic | envejecimiento estrés oxidativo inflamación enfermedades crónicas longevidad |
| url | http://medisur.sld.cu/index.php/medisur/article/view/3280 |
| work_keys_str_mv | AT angeljulioromerocabrera oxiinflammaginganewtheorywithpracticalimplications AT leocadiaamoreshernandez oxiinflammaginganewtheorywithpracticalimplications |