LTP after Stress: Up or Down?
When an organism is exposed to a stressful situation, corticosteroid levels in the brain rise. This rise has consequences for behavioral performance, including memory formation. Over the past decades, it has become clear that a rise in corticosteroid level is also accompanied by a reduction in hippo...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2007-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2007/93202 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832555440434577408 |
|---|---|
| author | Marian Joëls Harm J. Krugers |
| author_facet | Marian Joëls Harm J. Krugers |
| author_sort | Marian Joëls |
| collection | DOAJ |
| description | When an organism is exposed to a stressful situation, corticosteroid levels in the brain rise. This rise has consequences for behavioral performance, including memory formation. Over the past decades, it has become clear that a rise in corticosteroid level is also accompanied by a reduction in hippocampal long-term potentiation (LTP). Recent studies, however, indicate that stress does not lead to a universal suppression of LTP. Many factors, including the type of stress, the phase of the stress response, the area of investigation, type of LTP, and the life history of the organism determine in which direction LTP will be changed. |
| format | Article |
| id | doaj-art-144d27c529294f688ac3faadb30330b2 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-144d27c529294f688ac3faadb30330b22025-02-03T05:48:15ZengWileyNeural Plasticity2090-59041687-54432007-01-01200710.1155/2007/9320293202LTP after Stress: Up or Down?Marian Joëls0Harm J. Krugers1SILS-CNS, University of Amsterdam, SM Amsterdam 1098, The NetherlandsSILS-CNS, University of Amsterdam, SM Amsterdam 1098, The NetherlandsWhen an organism is exposed to a stressful situation, corticosteroid levels in the brain rise. This rise has consequences for behavioral performance, including memory formation. Over the past decades, it has become clear that a rise in corticosteroid level is also accompanied by a reduction in hippocampal long-term potentiation (LTP). Recent studies, however, indicate that stress does not lead to a universal suppression of LTP. Many factors, including the type of stress, the phase of the stress response, the area of investigation, type of LTP, and the life history of the organism determine in which direction LTP will be changed.http://dx.doi.org/10.1155/2007/93202 |
| spellingShingle | Marian Joëls Harm J. Krugers LTP after Stress: Up or Down? Neural Plasticity |
| title | LTP after Stress: Up or Down? |
| title_full | LTP after Stress: Up or Down? |
| title_fullStr | LTP after Stress: Up or Down? |
| title_full_unstemmed | LTP after Stress: Up or Down? |
| title_short | LTP after Stress: Up or Down? |
| title_sort | ltp after stress up or down |
| url | http://dx.doi.org/10.1155/2007/93202 |
| work_keys_str_mv | AT marianjoels ltpafterstressupordown AT harmjkrugers ltpafterstressupordown |