Application of Perclose ProGlide closure device in transbrachial endovascular intervention

Abstract This study aims to assess the clinical efficacy and feasibility of the Perclose ProGlide Suture-Mediated Closure System (Abbott Vascular, Redwood City, CA, USA) for transbrachial access. A total of 100 patients from July 2020 to December 2023 were included in this retrospective study. Among...

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Main Authors: Peng Zhao, Yao Yao, Quan Yang, Ning Wang, Liang Wang, Qianquan Ma, Wenchao Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-86896-x
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author Peng Zhao
Yao Yao
Quan Yang
Ning Wang
Liang Wang
Qianquan Ma
Wenchao Zhang
author_facet Peng Zhao
Yao Yao
Quan Yang
Ning Wang
Liang Wang
Qianquan Ma
Wenchao Zhang
author_sort Peng Zhao
collection DOAJ
description Abstract This study aims to assess the clinical efficacy and feasibility of the Perclose ProGlide Suture-Mediated Closure System (Abbott Vascular, Redwood City, CA, USA) for transbrachial access. A total of 100 patients from July 2020 to December 2023 were included in this retrospective study. Among them, 40 patients underwent ProGlide-guided suture closure following brachial artery (BA) puncture, while 60 patients received traditional manual compression. After successful ultrasound-guided puncture of the BA, a sheath of appropriate diameter (5–7F) was inserted. The Perclose ProGlide system was utilized in patients requiring ipsilateral upper limb intravenous infusion or dynamic blood pressure monitoring. All other patients underwent standard manual compression. No significant differences in major complications, including hematoma, pseudoaneurysm, or active bleeding, were observed between the two groups (P = 0.407). Additionally, there were no reported cases of arterial occlusion, ischemia, or venous thrombosis in either cohort. In the manual compression group, three patients required reintervention due to bleeding or hematoma, whereas no such incidents occurred in the ProGlide group (P = 0.151). Two patients in the manual compression group reported long-term numbness around the puncture site, while no similar neurological dysfunction was observed in the ProGlide group (P = 0.243). Although selection bias was present in this retrospective study, the Perclose ProGlide system presents a beneficial closure method for patients undergoing transbrachial access.
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spelling doaj-art-140f30d7dca547c1a8fb9d312fd9b27b2025-01-26T12:28:27ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-025-86896-xApplication of Perclose ProGlide closure device in transbrachial endovascular interventionPeng Zhao0Yao Yao1Quan Yang2Ning Wang3Liang Wang4Qianquan Ma5Wenchao Zhang6Department of Interventional Vascular Surgery, Peking University International Hospital, Peking UniversityDepartment of Neurosurgery, Peking University Third Hospital, Peking UniversityDepartment of Cardiology, Peking University International Hospital, Peking UniversityDepartment of Cardiology, Peking University International Hospital, Peking UniversityDepartment of Cardiology, Peking University International Hospital, Peking UniversityDepartment of Neurosurgery, Peking University Third Hospital, Peking UniversityDepartment of Cardiology, Peking University International Hospital, Peking UniversityAbstract This study aims to assess the clinical efficacy and feasibility of the Perclose ProGlide Suture-Mediated Closure System (Abbott Vascular, Redwood City, CA, USA) for transbrachial access. A total of 100 patients from July 2020 to December 2023 were included in this retrospective study. Among them, 40 patients underwent ProGlide-guided suture closure following brachial artery (BA) puncture, while 60 patients received traditional manual compression. After successful ultrasound-guided puncture of the BA, a sheath of appropriate diameter (5–7F) was inserted. The Perclose ProGlide system was utilized in patients requiring ipsilateral upper limb intravenous infusion or dynamic blood pressure monitoring. All other patients underwent standard manual compression. No significant differences in major complications, including hematoma, pseudoaneurysm, or active bleeding, were observed between the two groups (P = 0.407). Additionally, there were no reported cases of arterial occlusion, ischemia, or venous thrombosis in either cohort. In the manual compression group, three patients required reintervention due to bleeding or hematoma, whereas no such incidents occurred in the ProGlide group (P = 0.151). Two patients in the manual compression group reported long-term numbness around the puncture site, while no similar neurological dysfunction was observed in the ProGlide group (P = 0.243). Although selection bias was present in this retrospective study, the Perclose ProGlide system presents a beneficial closure method for patients undergoing transbrachial access.https://doi.org/10.1038/s41598-025-86896-x
spellingShingle Peng Zhao
Yao Yao
Quan Yang
Ning Wang
Liang Wang
Qianquan Ma
Wenchao Zhang
Application of Perclose ProGlide closure device in transbrachial endovascular intervention
Scientific Reports
title Application of Perclose ProGlide closure device in transbrachial endovascular intervention
title_full Application of Perclose ProGlide closure device in transbrachial endovascular intervention
title_fullStr Application of Perclose ProGlide closure device in transbrachial endovascular intervention
title_full_unstemmed Application of Perclose ProGlide closure device in transbrachial endovascular intervention
title_short Application of Perclose ProGlide closure device in transbrachial endovascular intervention
title_sort application of perclose proglide closure device in transbrachial endovascular intervention
url https://doi.org/10.1038/s41598-025-86896-x
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