Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO

USCOM is an ultrasound-based method which has been accepted for noninvasive hemodynamic monitoring in various clinical conditions (USCOM, Ultrasonic cardiac output monitoring). The present study aimed at comparing the accuracy of the USCOM device with that of the thermodilution technique in patients...

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Main Authors: Sophia Horster, Hans-Joachim Stemmler, Nina Strecker, Florian Brettner, Andreas Hausmann, Jitske Cnossen, Klaus G. Parhofer, Thomas Nickel, Sandra Geiger
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/270631
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author Sophia Horster
Hans-Joachim Stemmler
Nina Strecker
Florian Brettner
Andreas Hausmann
Jitske Cnossen
Klaus G. Parhofer
Thomas Nickel
Sandra Geiger
author_facet Sophia Horster
Hans-Joachim Stemmler
Nina Strecker
Florian Brettner
Andreas Hausmann
Jitske Cnossen
Klaus G. Parhofer
Thomas Nickel
Sandra Geiger
author_sort Sophia Horster
collection DOAJ
description USCOM is an ultrasound-based method which has been accepted for noninvasive hemodynamic monitoring in various clinical conditions (USCOM, Ultrasonic cardiac output monitoring). The present study aimed at comparing the accuracy of the USCOM device with that of the thermodilution technique in patients with septicemia. We conducted a prospective observational study in a medical but noncardiological ICU of a university hospital. Septic adult patients (median age 55 years, median SAPS-II-Score 43 points) on mechanical ventilation and catecholamine support were monitored with USCOM and PiCCO (𝑛=70). Seventy paired left-sided CO measurements (transaortic access = COUS-A) were obtained. The mean COUS-A were 6.55 l/min (±2.19) versus COPiCCO 6.5 l/min (±2.18). The correlation coefficient was 𝑟=0.89. Comparison by Bland-Altman analysis revealed a bias of −0.36 l/min (±0.99 l/min) leading to a mean percentage error of 29%. USCOM is a feasible and rapid method to evaluate CO in septic patients. USCOM does reliably represent CO values as compared to the reference technique based on thermodilution (PiCCO). It seems to be appropriate in situations where CO measurements are most pertinent to patient management.
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institution Kabale University
issn 2090-1305
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spelling doaj-art-14030c6196964aa7a491818cd633a2892025-02-03T05:57:31ZengWileyCritical Care Research and Practice2090-13052090-13132012-01-01201210.1155/2012/270631270631Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCOSophia Horster0Hans-Joachim Stemmler1Nina Strecker2Florian Brettner3Andreas Hausmann4Jitske Cnossen5Klaus G. Parhofer6Thomas Nickel7Sandra Geiger8Medical Department II, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department III, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department III, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyDepartment of Anesthesia II, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department III, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department III, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department II, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department I, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyMedical Department III, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistraße 15, 81377 Munich, GermanyUSCOM is an ultrasound-based method which has been accepted for noninvasive hemodynamic monitoring in various clinical conditions (USCOM, Ultrasonic cardiac output monitoring). The present study aimed at comparing the accuracy of the USCOM device with that of the thermodilution technique in patients with septicemia. We conducted a prospective observational study in a medical but noncardiological ICU of a university hospital. Septic adult patients (median age 55 years, median SAPS-II-Score 43 points) on mechanical ventilation and catecholamine support were monitored with USCOM and PiCCO (𝑛=70). Seventy paired left-sided CO measurements (transaortic access = COUS-A) were obtained. The mean COUS-A were 6.55 l/min (±2.19) versus COPiCCO 6.5 l/min (±2.18). The correlation coefficient was 𝑟=0.89. Comparison by Bland-Altman analysis revealed a bias of −0.36 l/min (±0.99 l/min) leading to a mean percentage error of 29%. USCOM is a feasible and rapid method to evaluate CO in septic patients. USCOM does reliably represent CO values as compared to the reference technique based on thermodilution (PiCCO). It seems to be appropriate in situations where CO measurements are most pertinent to patient management.http://dx.doi.org/10.1155/2012/270631
spellingShingle Sophia Horster
Hans-Joachim Stemmler
Nina Strecker
Florian Brettner
Andreas Hausmann
Jitske Cnossen
Klaus G. Parhofer
Thomas Nickel
Sandra Geiger
Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
Critical Care Research and Practice
title Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
title_full Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
title_fullStr Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
title_full_unstemmed Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
title_short Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
title_sort cardiac output measurements in septic patients comparing the accuracy of uscom to picco
url http://dx.doi.org/10.1155/2012/270631
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