Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review
Listeria monocytogenes infections have been described in patients with diverse types of malignancy, especially leukemia. We report the case of a 65-year-old man with previously untreated hairy cell leukemia characterized by CD5 positivity and trisomy 12 (3% of blood lymphocytes) who developed bacter...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/5616898 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850227407508733952 |
|---|---|
| author | James C. Barton Hayward S. Edmunds |
| author_facet | James C. Barton Hayward S. Edmunds |
| author_sort | James C. Barton |
| collection | DOAJ |
| description | Listeria monocytogenes infections have been described in patients with diverse types of malignancy, especially leukemia. We report the case of a 65-year-old man with previously untreated hairy cell leukemia characterized by CD5 positivity and trisomy 12 (3% of blood lymphocytes) who developed bacteremia due to L. monocytogenes serotype 1/2b. We summarize clinical features and treatment of this patient and five previously reported patients with hairy cell leukemia who also had L. monocytogenes infections. All six patients were men. Their mean age at infection diagnosis was 70 y. Three men had undergone splenectomy 4–11 y before they developed L. monocytogenes infection. The central nervous system was the primary site of infection in four men. Bacteremia alone occurred in two other men. At diagnosis of infection, one man was receiving antileukemia chemotherapy and another man was receiving treatment for Kaposi’s sarcoma. Two other patients had other comorbid conditions. All six men recovered from their infections. |
| format | Article |
| id | doaj-art-13f38e8a81114da9a0b528093ea549c7 |
| institution | OA Journals |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-13f38e8a81114da9a0b528093ea549c72025-08-20T02:04:51ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/56168985616898Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature ReviewJames C. Barton0Hayward S. Edmunds1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USACunningham Pathology Associates, Birmingham, AL, USAListeria monocytogenes infections have been described in patients with diverse types of malignancy, especially leukemia. We report the case of a 65-year-old man with previously untreated hairy cell leukemia characterized by CD5 positivity and trisomy 12 (3% of blood lymphocytes) who developed bacteremia due to L. monocytogenes serotype 1/2b. We summarize clinical features and treatment of this patient and five previously reported patients with hairy cell leukemia who also had L. monocytogenes infections. All six patients were men. Their mean age at infection diagnosis was 70 y. Three men had undergone splenectomy 4–11 y before they developed L. monocytogenes infection. The central nervous system was the primary site of infection in four men. Bacteremia alone occurred in two other men. At diagnosis of infection, one man was receiving antileukemia chemotherapy and another man was receiving treatment for Kaposi’s sarcoma. Two other patients had other comorbid conditions. All six men recovered from their infections.http://dx.doi.org/10.1155/2018/5616898 |
| spellingShingle | James C. Barton Hayward S. Edmunds Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review Case Reports in Hematology |
| title | Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review |
| title_full | Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review |
| title_fullStr | Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review |
| title_full_unstemmed | Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review |
| title_short | Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review |
| title_sort | listeria monocytogenes infection in hairy cell leukemia a case report and literature review |
| url | http://dx.doi.org/10.1155/2018/5616898 |
| work_keys_str_mv | AT jamescbarton listeriamonocytogenesinfectioninhairycellleukemiaacasereportandliteraturereview AT haywardsedmunds listeriamonocytogenesinfectioninhairycellleukemiaacasereportandliteraturereview |