Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report
Background: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2024-10-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | https://actamedindones.org/index.php/ijim/article/view/2123 |
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| author | Hamzah Shatri Nabella Qisthina Laksita Dewi Vinandia Irvianita Edward Faisal Rudi Putranto |
| author_facet | Hamzah Shatri Nabella Qisthina Laksita Dewi Vinandia Irvianita Edward Faisal Rudi Putranto |
| author_sort | Hamzah Shatri |
| collection | DOAJ |
| description | Background: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy. This evidence-based case report (EBCR) aims to determine the role of antidepressants in acute coronary syndrome patients. Methods: Literature searching was performed using online databases such as EBSCO, Embase, PubMed, ClinicalKey, and ScienceDirect according to clinical questions. The studies were selected based on the suitability of the inclusion and exclusion criteria followed by critical appraisal. Results: In patients with ACS, antidepressants do not affect mortality but may reduce rehospitalization. In patients with ACS and depression who received antidepressants, there is a reduced risk of myocardial infarction (MI) recurrence. In post-ACS patients, the use of antidepressants is associated with a reduced risk of recurrent MI. Conclusion: In ACS patients, antidepressants do not affect mortality, but can reduce the incidence of myocardial reinfarction. |
| format | Article |
| id | doaj-art-13edb54b93c647f9862dd4837adb3eab |
| institution | Kabale University |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-13edb54b93c647f9862dd4837adb3eab2025-01-27T04:12:06ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01564705Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case ReportHamzah Shatri0Nabella Qisthina Laksita Dewi1Vinandia Irvianita2Edward Faisal3Rudi Putranto41. Division of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 2. Clinical Epidemiology in Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Division of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Psychosomatic and Palliative, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaBackground: Acute coronary syndrome (ACS) and depression are related to each other. Detection and proper treatment of these conditions can improve functional ability and quality of life. However, there is still controversy in this population regarding the use, safety, and efficacy of antidepressant pharmacotherapy. This evidence-based case report (EBCR) aims to determine the role of antidepressants in acute coronary syndrome patients. Methods: Literature searching was performed using online databases such as EBSCO, Embase, PubMed, ClinicalKey, and ScienceDirect according to clinical questions. The studies were selected based on the suitability of the inclusion and exclusion criteria followed by critical appraisal. Results: In patients with ACS, antidepressants do not affect mortality but may reduce rehospitalization. In patients with ACS and depression who received antidepressants, there is a reduced risk of myocardial infarction (MI) recurrence. In post-ACS patients, the use of antidepressants is associated with a reduced risk of recurrent MI. Conclusion: In ACS patients, antidepressants do not affect mortality, but can reduce the incidence of myocardial reinfarction.https://actamedindones.org/index.php/ijim/article/view/2123acute coronary syndromeantidepressantcardiovascular eventmortality |
| spellingShingle | Hamzah Shatri Nabella Qisthina Laksita Dewi Vinandia Irvianita Edward Faisal Rudi Putranto Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report Acta Medica Indonesiana acute coronary syndrome antidepressant cardiovascular event mortality |
| title | Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report |
| title_full | Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report |
| title_fullStr | Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report |
| title_full_unstemmed | Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report |
| title_short | Role of Antidepressants in Acute Coronary Syndrome: An Evidence-Based Case Report |
| title_sort | role of antidepressants in acute coronary syndrome an evidence based case report |
| topic | acute coronary syndrome antidepressant cardiovascular event mortality |
| url | https://actamedindones.org/index.php/ijim/article/view/2123 |
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