Red blood cell-tumor cell interactions promote tumor cell progression

Abstract A critical step in the metastatic cascade is the survival of circulating tumor cells (CTCs) within the bloodstream. Although interactions between CTCs and various hematopoietic cells have been described, the role of red blood cells (RBCs) remains underexplored. This study investigated the i...

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Main Authors:	Thais Pereira-Veiga, Celso Yáñez-Gómez, Aleksi Pekkarinen, Carmen Abuín, Christine Blechner, Miriam González-Conde, Christian Mess, Sabine Vidal-y-Sy, Ayham Moustafa, Bente Siebels, Ana B. Dávila-Ibáñez, Pablo Cabezas-Sainz, Maider Santos, Laura Sánchez, Joao Gorgulho, Julian Götze, Kira Meißner, Juan Cueva, Patricia Palacios, Alexandra Cortegoso, Teresa Curiel, Carmela Rodríguez, Marta Carmona, Luis León-Mateos, Alicia Abalo, Laura Muinelo-Romay, Sven Peine, Milena Schmidt, Nadine Heuer-Olewinski, Martin Reck, Mustafa Abdo, Katrin Lamszus, Alexander T. Bauer, Rafael López-López, Klaus Pantel, Sabine Windhorst, Harriet Wikman, Clotilde Costa
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	Red blood cells (RBCs) Breast cancer Lung cancer Circulating tumor cells Liquid biopsy Actin remodeling
Online Access:	https://doi.org/10.1186/s13046-025-03376-w
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Red blood cell-tumor cell interactions promote tumor cell progression

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