The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use

Objective. To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C). Methods. Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and...

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Main Authors: Carla E. Ransom, Jeanette R. Chin, Hilary A. Roeder, Tammy R. Sinclair, R. Phillips Heine, Amy P. Murtha
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2011/286483
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author Carla E. Ransom
Jeanette R. Chin
Hilary A. Roeder
Tammy R. Sinclair
R. Phillips Heine
Amy P. Murtha
author_facet Carla E. Ransom
Jeanette R. Chin
Hilary A. Roeder
Tammy R. Sinclair
R. Phillips Heine
Amy P. Murtha
author_sort Carla E. Ransom
collection DOAJ
description Objective. To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C). Methods. Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and clinical characteristics were abstracted. Results. Of 104 eligible subjects, 82 (78.8%) were offered 17-OHP-C. Of these, thirty-four (41.5%) declined. The median gestational age of the most recent preterm delivery was significantly lower among subjects who accepted 17-OHP-C as compared to those who declined (28.7 vs. 34.0 weeks, 𝑃=.02) and in subjects offered 17-OHP-C compared to those not offered 17-OHP-C (30.2 vs. 36.0 weeks, 𝑃=.03). Subjects not offered 17-OHP-C were more likely to have had an interval term delivery (31.8% vs. 9.7%, 𝑃=.009) Conclusion. Women with earlier preterm deliveries were more likely to be offered and accept 17-OHP-C. Prior obstetric history may influence both providers' and patients' willingness to discuss and/or accept 17-OHP-C.
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spelling doaj-art-13e2f2472df84878b9f653d67797d8702025-02-03T06:07:31ZengWileyJournal of Pregnancy2090-27272090-27352011-01-01201110.1155/2011/286483286483The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate UseCarla E. Ransom0Jeanette R. Chin1Hilary A. Roeder2Tammy R. Sinclair3R. Phillips Heine4Amy P. Murtha5Department of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USADepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT. 84132, USADepartment of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USADepartment of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USADepartment of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USADepartment of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USAObjective. To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C). Methods. Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and clinical characteristics were abstracted. Results. Of 104 eligible subjects, 82 (78.8%) were offered 17-OHP-C. Of these, thirty-four (41.5%) declined. The median gestational age of the most recent preterm delivery was significantly lower among subjects who accepted 17-OHP-C as compared to those who declined (28.7 vs. 34.0 weeks, 𝑃=.02) and in subjects offered 17-OHP-C compared to those not offered 17-OHP-C (30.2 vs. 36.0 weeks, 𝑃=.03). Subjects not offered 17-OHP-C were more likely to have had an interval term delivery (31.8% vs. 9.7%, 𝑃=.009) Conclusion. Women with earlier preterm deliveries were more likely to be offered and accept 17-OHP-C. Prior obstetric history may influence both providers' and patients' willingness to discuss and/or accept 17-OHP-C.http://dx.doi.org/10.1155/2011/286483
spellingShingle Carla E. Ransom
Jeanette R. Chin
Hilary A. Roeder
Tammy R. Sinclair
R. Phillips Heine
Amy P. Murtha
The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
Journal of Pregnancy
title The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
title_full The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
title_fullStr The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
title_full_unstemmed The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
title_short The Influence of Prior Obstetrical History on Current 17-Hydroxyprogesterone Caproate Use
title_sort influence of prior obstetrical history on current 17 hydroxyprogesterone caproate use
url http://dx.doi.org/10.1155/2011/286483
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