Evolution of intrinsic disorder in the structural domains of viral and cellular proteomes

Abstract Intrinsically disordered regions are flexible regions that complement the typical structured regions of proteins. Little is known however about their evolution. Here we leverage a comparative and evolutionary genomics approach to analyze intrinsic disorder in the structural domains of thous...

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Bibliographic Details
Main Authors: Fizza Mughal, Gustavo Caetano-Anollés
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-86045-4
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