Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products
With incredible bioactivities and fascinating structural complexities, tetramic acid- (TA-) containing natural products have attracted favorable attention among the organic chemistry community. Although the construction of the TA core is usually straightforward, the intricate C3-side chain sometimes...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2016/8510278 |
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| _version_ | 1832563541280817152 |
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| author | Wen-Ju Bai Chen Lu Xiqing Wang |
| author_facet | Wen-Ju Bai Chen Lu Xiqing Wang |
| author_sort | Wen-Ju Bai |
| collection | DOAJ |
| description | With incredible bioactivities and fascinating structural complexities, tetramic acid- (TA-) containing natural products have attracted favorable attention among the organic chemistry community. Although the construction of the TA core is usually straightforward, the intricate C3-side chain sometimes asks for some deliberative strategy so as to fulfill an elegant total synthesis. This review mainly covers some exceptional synthetic examples for each type of natural product in recent years, showcasing the great achievements as well as unsettled obstacles in this area, in the hope of accelerating the synthetic and biological investigations for this unique type of natural product. |
| format | Article |
| id | doaj-art-13c67e06c7a240efb6cecd73a6f2c968 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-13c67e06c7a240efb6cecd73a6f2c9682025-02-03T01:13:07ZengWileyJournal of Chemistry2090-90632090-90712016-01-01201610.1155/2016/85102788510278Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural ProductsWen-Ju Bai0Chen Lu1Xiqing Wang2Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USACollege of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu 225009, ChinaCollege of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu 225009, ChinaWith incredible bioactivities and fascinating structural complexities, tetramic acid- (TA-) containing natural products have attracted favorable attention among the organic chemistry community. Although the construction of the TA core is usually straightforward, the intricate C3-side chain sometimes asks for some deliberative strategy so as to fulfill an elegant total synthesis. This review mainly covers some exceptional synthetic examples for each type of natural product in recent years, showcasing the great achievements as well as unsettled obstacles in this area, in the hope of accelerating the synthetic and biological investigations for this unique type of natural product.http://dx.doi.org/10.1155/2016/8510278 |
| spellingShingle | Wen-Ju Bai Chen Lu Xiqing Wang Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products Journal of Chemistry |
| title | Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products |
| title_full | Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products |
| title_fullStr | Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products |
| title_full_unstemmed | Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products |
| title_short | Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products |
| title_sort | recent advances in the total synthesis of tetramic acid containing natural products |
| url | http://dx.doi.org/10.1155/2016/8510278 |
| work_keys_str_mv | AT wenjubai recentadvancesinthetotalsynthesisoftetramicacidcontainingnaturalproducts AT chenlu recentadvancesinthetotalsynthesisoftetramicacidcontainingnaturalproducts AT xiqingwang recentadvancesinthetotalsynthesisoftetramicacidcontainingnaturalproducts |