TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms

Tumor necrosis factor (TNF) tolerance in monocytes and macrophages means that preexposure to TNF reduces the sensitivity in these cells to a subsequent restimulation with this cytokine. Differential effects arise following preincubation with both low and high doses of TNF resulting in absolute as we...

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Bibliographic Details
Main Authors: René Huber, Rolf Bikker, Bastian Welz, Martin Christmann, Korbinian Brand
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2017/9570129
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