Hypercapnia from Physiology to Practice

Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an incr...

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Main Authors: Amilkar Almanza-Hurtado, Camilo Polanco Guerra, María Cristina Martínez-Ávila, Diana Borré-Naranjo, Tomás Rodríguez-Yanez, Carmelo Dueñas-Castell
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Clinical Practice
Online Access:http://dx.doi.org/10.1155/2022/2635616
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author Amilkar Almanza-Hurtado
Camilo Polanco Guerra
María Cristina Martínez-Ávila
Diana Borré-Naranjo
Tomás Rodríguez-Yanez
Carmelo Dueñas-Castell
author_facet Amilkar Almanza-Hurtado
Camilo Polanco Guerra
María Cristina Martínez-Ávila
Diana Borré-Naranjo
Tomás Rodríguez-Yanez
Carmelo Dueñas-Castell
author_sort Amilkar Almanza-Hurtado
collection DOAJ
description Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an increase in dead space, or an increase in carbon dioxide (CO2) production per sec. They generate a compromise at the cardiovascular, cerebral, metabolic, and respiratory levels with a high burden of morbidity and mortality. It is essential to know the triggers to provide therapy directed at the primary cause and avoid possible complications.
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id doaj-art-13b9e1b7b7fb405d8955f0042b260c56
institution Kabale University
issn 1742-1241
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series International Journal of Clinical Practice
spelling doaj-art-13b9e1b7b7fb405d8955f0042b260c562025-02-03T06:00:27ZengWileyInternational Journal of Clinical Practice1742-12412022-01-01202210.1155/2022/2635616Hypercapnia from Physiology to PracticeAmilkar Almanza-Hurtado0Camilo Polanco Guerra1María Cristina Martínez-Ávila2Diana Borré-Naranjo3Tomás Rodríguez-Yanez4Carmelo Dueñas-Castell5Intensive Care UnitMedicine ProgramEpidemiology and Public HealthIntensive Care UnitIntensive Care UnitIntensive Care UnitAcute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an increase in dead space, or an increase in carbon dioxide (CO2) production per sec. They generate a compromise at the cardiovascular, cerebral, metabolic, and respiratory levels with a high burden of morbidity and mortality. It is essential to know the triggers to provide therapy directed at the primary cause and avoid possible complications.http://dx.doi.org/10.1155/2022/2635616
spellingShingle Amilkar Almanza-Hurtado
Camilo Polanco Guerra
María Cristina Martínez-Ávila
Diana Borré-Naranjo
Tomás Rodríguez-Yanez
Carmelo Dueñas-Castell
Hypercapnia from Physiology to Practice
International Journal of Clinical Practice
title Hypercapnia from Physiology to Practice
title_full Hypercapnia from Physiology to Practice
title_fullStr Hypercapnia from Physiology to Practice
title_full_unstemmed Hypercapnia from Physiology to Practice
title_short Hypercapnia from Physiology to Practice
title_sort hypercapnia from physiology to practice
url http://dx.doi.org/10.1155/2022/2635616
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