Hypercapnia from Physiology to Practice
Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an incr...
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Format: | Article |
Language: | English |
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Wiley
2022-01-01
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Series: | International Journal of Clinical Practice |
Online Access: | http://dx.doi.org/10.1155/2022/2635616 |
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author | Amilkar Almanza-Hurtado Camilo Polanco Guerra María Cristina Martínez-Ávila Diana Borré-Naranjo Tomás Rodríguez-Yanez Carmelo Dueñas-Castell |
author_facet | Amilkar Almanza-Hurtado Camilo Polanco Guerra María Cristina Martínez-Ávila Diana Borré-Naranjo Tomás Rodríguez-Yanez Carmelo Dueñas-Castell |
author_sort | Amilkar Almanza-Hurtado |
collection | DOAJ |
description | Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an increase in dead space, or an increase in carbon dioxide (CO2) production per sec. They generate a compromise at the cardiovascular, cerebral, metabolic, and respiratory levels with a high burden of morbidity and mortality. It is essential to know the triggers to provide therapy directed at the primary cause and avoid possible complications. |
format | Article |
id | doaj-art-13b9e1b7b7fb405d8955f0042b260c56 |
institution | Kabale University |
issn | 1742-1241 |
language | English |
publishDate | 2022-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Clinical Practice |
spelling | doaj-art-13b9e1b7b7fb405d8955f0042b260c562025-02-03T06:00:27ZengWileyInternational Journal of Clinical Practice1742-12412022-01-01202210.1155/2022/2635616Hypercapnia from Physiology to PracticeAmilkar Almanza-Hurtado0Camilo Polanco Guerra1María Cristina Martínez-Ávila2Diana Borré-Naranjo3Tomás Rodríguez-Yanez4Carmelo Dueñas-Castell5Intensive Care UnitMedicine ProgramEpidemiology and Public HealthIntensive Care UnitIntensive Care UnitIntensive Care UnitAcute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream. The pathophysiological mechanisms of hypercapnia include the decrease in minute volume, an increase in dead space, or an increase in carbon dioxide (CO2) production per sec. They generate a compromise at the cardiovascular, cerebral, metabolic, and respiratory levels with a high burden of morbidity and mortality. It is essential to know the triggers to provide therapy directed at the primary cause and avoid possible complications.http://dx.doi.org/10.1155/2022/2635616 |
spellingShingle | Amilkar Almanza-Hurtado Camilo Polanco Guerra María Cristina Martínez-Ávila Diana Borré-Naranjo Tomás Rodríguez-Yanez Carmelo Dueñas-Castell Hypercapnia from Physiology to Practice International Journal of Clinical Practice |
title | Hypercapnia from Physiology to Practice |
title_full | Hypercapnia from Physiology to Practice |
title_fullStr | Hypercapnia from Physiology to Practice |
title_full_unstemmed | Hypercapnia from Physiology to Practice |
title_short | Hypercapnia from Physiology to Practice |
title_sort | hypercapnia from physiology to practice |
url | http://dx.doi.org/10.1155/2022/2635616 |
work_keys_str_mv | AT amilkaralmanzahurtado hypercapniafromphysiologytopractice AT camilopolancoguerra hypercapniafromphysiologytopractice AT mariacristinamartinezavila hypercapniafromphysiologytopractice AT dianaborrenaranjo hypercapniafromphysiologytopractice AT tomasrodriguezyanez hypercapniafromphysiologytopractice AT carmeloduenascastell hypercapniafromphysiologytopractice |