Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit

Right heart thrombus in transit clot (RHTT) associated with a pulmonary thromboembolism (PTE) is a rare but potentially fatal diagnosis. Early diagnosis and immediate intervention are crucial. This report describes the case of a healthy, physically active 32-year-old female who presented 19 days pos...

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Main Authors: Cynthia Mardinger, Paul J. E. Boiteau, John B. Kortbeek
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/7561986
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author Cynthia Mardinger
Paul J. E. Boiteau
John B. Kortbeek
author_facet Cynthia Mardinger
Paul J. E. Boiteau
John B. Kortbeek
author_sort Cynthia Mardinger
collection DOAJ
description Right heart thrombus in transit clot (RHTT) associated with a pulmonary thromboembolism (PTE) is a rare but potentially fatal diagnosis. Early diagnosis and immediate intervention are crucial. This report describes the case of a healthy, physically active 32-year-old female who presented 19 days postoperatively, following an anterior cruciate ligament reconstruction and partial lateral meniscectomy with a saddle PE, RHTT, and right ventricular (RV) strain. The patient received half of the standard dose of intravenous tissue plasminogen activator (TPA) in combination with anticoagulation and survived. Case reports of RHTT will inform future studies designed to evaluate whether and when thrombolysis should be administered.
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spelling doaj-art-1398076481be424ab50b60ea2fb8e8a42025-02-03T01:27:04ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/75619867561986Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in TransitCynthia Mardinger0Paul J. E. Boiteau1John B. Kortbeek2Cumming School of Medicine, University of Calgary, Foothills Medical Centre, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, CanadaDepartment of Critical Care Medicine, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, CanadaDepartment of Critical Care Medicine, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, CanadaRight heart thrombus in transit clot (RHTT) associated with a pulmonary thromboembolism (PTE) is a rare but potentially fatal diagnosis. Early diagnosis and immediate intervention are crucial. This report describes the case of a healthy, physically active 32-year-old female who presented 19 days postoperatively, following an anterior cruciate ligament reconstruction and partial lateral meniscectomy with a saddle PE, RHTT, and right ventricular (RV) strain. The patient received half of the standard dose of intravenous tissue plasminogen activator (TPA) in combination with anticoagulation and survived. Case reports of RHTT will inform future studies designed to evaluate whether and when thrombolysis should be administered.http://dx.doi.org/10.1155/2020/7561986
spellingShingle Cynthia Mardinger
Paul J. E. Boiteau
John B. Kortbeek
Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
Case Reports in Medicine
title Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
title_full Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
title_fullStr Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
title_full_unstemmed Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
title_short Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
title_sort thrombolysis of postoperative acute pulmonary embolism with a thrombus in transit
url http://dx.doi.org/10.1155/2020/7561986
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